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DateTitleAuthor(s)Full text
2004Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence: Platelet aggregation and relaxant activitiesAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Roumelioti, P.; Mavromoustakos, Thomas; Mihailescu, S.; Paredes-Carbajal, M. C.; Mascher, D.; Matsoukas, J.
2001Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence with fixed conformations of pharmacophoric groups: Importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimeticsAlexopoulos, K.; Panagiotopoulos, D.; Mavromoustakos, Thomas; Fatseas, P.; Paredes-Carbajal, M. C.; Mascher, D.; Mihailescu, S.; Matsoukas, J.
1999Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffoldAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Smith, J.; Mavromoustakos, Thomas; Saifeddine, M.; Moore, G.; Hollenberg, M.; Matsoukas, J.
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