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DateTitleAuthor(s)Full text
2005Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylaseWatson, K. A.; Chrysina, Evangelia D.; Tsitsanou, K. E.; Zographos, Spyros E.; Archontis, G.; Fleet, G. W. J.; Oikonomakos, Nikos G.
1999Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structureTsitsanou, K. E.; Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Gregoriou, M.; Watson, K. A.; Johnson, L. N.; Fleet, G. W. J.
1998The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 angstrom resolution and 100 K: The role of the water structure and its contribution to bindingGregoriou, M.; Noble, M. E. M.; Watson, K. A.; Garman, E. F.; Krulle, T. M.; De la Fuente, C.; Fleet, G. W. J.; Oikonomakos, Nikos G.; Johnson, L. N.
1998Sugar mimics from sugar lactonesFleet, G. W. J.; Estevez, J. C.; Smith, M. D.; Bleriot, Y.; de la Fuente, C.; Krulle, T. M.; Besra, G. S.; Brennan, P. J.; Nash, R. J.; Johnson, L. N.; Oikonomakos, Nikos G.; Stalmans, W.
1997Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylasedelaFuente, C.; Krulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1997Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylateKrulle, T.; delaFuente, C.; Pickering, L.; Aplin, R. T.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Nash, R. J.; Griffiths, R. C.; Fleet, G. W. J.
1997Stereospecific synthesis of spirohydantoins of beta-glucopyranose: Inhibitors of glycogen phosphorylaseKrulle, T. M.; delaFuente, C.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
19967-carbon mimics of D-glucose and L-fucose: Activation by 6R-, and inactivation by 6S, -6C-methylglucose of glycogen synthase: Inhibition of glucokinase and/or glucose-6-phosphataseBleriot, Y.; Smelt, K. H.; Cadefau, J.; Bollen, M.; Stalmans, W.; Biggadike, K.; Johnson, L. N.; Oikonomakos, Nikos G.; Lane, A. L.; Crook, S.; Watkin, D. J.; Fleet, G. W. J.
1996Glucofuranose analogues of hydantocidinBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Johnson, L. N.; Crook, S.; Lilley, Pmdq; Watkin, D. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1996A galactopyranose analogue of hydantocidinBrandstetter, T. W.; Wormald, M. R.; Dwek, R. A.; Butters, T. D.; Platt, F. M.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1996alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptidesBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Cooper, R. I.; Watkin, D. J.; Oikonomakos, Nikos G.; Johnson, L. N.; Fleet, G. W. J.
1995Specific-Inhibition of Glycogen-Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of GlucopyranoseKrulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Crook, S.; Watkin, D. J.; Griffiths, R. C.; Nash, R. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1995Spirohydantoins of Glucofuranose - Analogs of HydantocidinBrandstetter, T. W.; Kim, Y. H.; Son, J. C.; Taylor, H. M.; Lilley, P. M. D.; Watkin, D. J.; Johnson, L. N.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1995Potent Inhibition of Glycogen-Phosphorylase by a Spirohydantoin of Glucopyranose - First Pyranose Analogs of HydantocidinBichard, C. J. F.; Mitchell, E. P.; Wormald, M. R.; Watson, K. A.; Johnson, L. N.; Zographos, Spyros E.; Koutra, D. D.; Oikonomakos, Nikos G.; Fleet, G. W. J.
1995Glucose Analog Inhibitors of Glycogen-Phosphorylase - from Crystallographic Analysis to Drug Prediction Using Grid Force-Field and Golpe Variable SelectionWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Cruciani, G.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Oikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.
1995N-Acetyl-Beta-D-Glucopyranosylamine - a Potent T-State Inhibitor of Glycogen-Phosphorylase - a Comparison with Alpha-D-GlucoseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Watson, K. A.; Johnson, L. N.; Bichard, C. J. F.; Fleet, G. W. J.; Acharya, K. R.
1994The design of potential antidiabetic drugs: Experimental investigation of a number of ?-D-glucose analogue inhibitors of glycogen phosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
1994The Design of Potential Antidiabetic Drugs - Experimental Investigation of a Number of Beta-D-Glucose Analog Inhibitors of Glycogen-PhosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
1993X-Ray Crystallographic Analysis of 2,6-Anhydro-N-Methyl-D-Glycero-D-Ido-Heptonamide - the 1st Example of a Simple Glucose Analog with a Skew Boat StructureWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Ford, P.; Watkin, D. J.; Oikonomakos, Nikos G.
Showing results 1 to 19 of 19



 

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