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DateTitleAuthor(s)Full text
2006Design, synthesis, and molecular modeling of a novel amide-linked cyclic GnRH analogue cyclo(4-9)[Lys(4),D-Trp(6),Glu(9)]GnRH: Stimulation of gonadotropin gene expressionKeramida, M. K.; Tselios, T.; Mantzourani, E.; Papazisis, K.; Mavromoustakos, Thomas; Klaussen, C.; Agelis, G.; Deraos, S.; Friligou, I.; Habibi, H.; Matsoukas, J.
2006Structure elucidation and conformational study of V8 - A novel synthetic non peptide AT(1) antagonistZoumpoulakis, Panagiotis; Politi, A.; Grdadolnik, S. G.; Matsoukas, J.; Mavromoustakos, Thomas
2005Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: Enhanced stability and biological properties of mimics render them a potentially new class of immunomodulatorsMatsoukas, J.; Apostolopoulos, V.; Kalbacher, H.; Papini, A. M.; Tselios, T.; Chatzantoni, K.; Biagioli, T.; Lolli, F.; Deraos, S.; Papathanassopoulos, P.; Troganis, A.; Mantzourani, E.; Mavromoustakos, Thomas; Mouzaki, A.
2004Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence: Platelet aggregation and relaxant activitiesAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Roumelioti, P.; Mavromoustakos, Thomas; Mihailescu, S.; Paredes-Carbajal, M. C.; Mascher, D.; Matsoukas, J.
2004Conformation and bioactivity. Design and discovery of novel antihypertensive drugsMavromoustakos, Thomas; Zervou, Maria; Zoumpoulakis, Panagiotis; Kyrikou, I.; Benetis, N. P.; Polevaya, L.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P. M.; Kolocouris, A.; Vlahakos, D.; Grdadolnik, S. G.; Matsoukas, J.
2004Hematocrit-lowering effect following inactivation of renin-angiotensin system with angiotensin converting enzyme inhibitors and angiotensin receptor blockersMarathias, K. P.; Agroyannis, B.; Mavromoustakos, Thomas; Matsoukas, J.; Vlahakos, D. V.
2003Design, conformation and bioactivity of novel angiotensin II receptor antagonistsMavromoustakos, Thomas; Zoumpoulakis, Panagiotis; Roumelioti, P.; Giatas, N.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Matsoukas, J.
2003Conformation and bioactivity: design and discovery of novel antihypertensive drugsMavromoustakos, Thomas; Zervou, Maria; Zoumpoulakis, Panagiotis; Kyrikou, I.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P.M.; Kamoutsis, C.; Dimitriou, D.; Pitsas, A.; Matsoukas, J.
2002Structure elucidation and conformational properties of eprosartan a non peptide Angiotensin II AT(1) antagonistZoumpoulakis, Panagiotis; Grdadolnik, S. G.; Matsoukas, J.; Mavromoustakos, Thomas
2002Design, synthesis and biological evaluation of cyclic Angiotensin II analogues with 3,5 side-chain bridges: Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonistsRoumelioti, P.; Polevaya, L.; Zoumpoulakis, Panagiotis; Giatas, N.; Mutule, I.; Keivish, T.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Kremastinos, D.; Grdadolnik, S. G.; Mavromoustakos, Thomas; Matsoukas, J.
2002Applications of peptide mimetics in cancerApostolopoulos, V.; Matsoukas, J.; Plebanski, A.; Mavromoustakos, Thomas
2002Antagonistic effects of human cyclic MBP87-99 altered peptide ligands in experimental allergic encephalomyelitis and human T-cell proliferationTselios, T.; Apostolopoulos, V.; Daliani, I.; Deraos, S.; Grdadolnik, S.; Mavromoustakos, Thomas; Melachrinou, M.; Thymianou, S.; Probert, L.; Mouzaki, A.; Matsoukas, J.
2001Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence with fixed conformations of pharmacophoric groups: Importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimeticsAlexopoulos, K.; Panagiotopoulos, D.; Mavromoustakos, Thomas; Fatseas, P.; Paredes-Carbajal, M. C.; Mascher, D.; Mihailescu, S.; Matsoukas, J.
2001Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*-pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonistsPolevaya, L.; Mavromoustakos, Thomas; Zoumpoulakis, Panagiotis; Grdadolnik, S. G.; Roumelioti, P.; Giatas, N.; Mutule, I.; Keivish, T.; Vlahakos, D. V.; Iliodromitis, E. K.; Kremastinos, D. T.; Matsoukas, J.
2001Antihypertensive drugs that act on Renin-Angiotensin System with emphasis in AT(1) antagonistsMavromoustakos, Thomas; Apostolopoulos, V.; Matsoukas, J.
2000Treatment of experimental allergic encephalomyelitis (EAE) induced by guinea pig myelin basic protein epitope 72-85 with a human MBP87-99 analogue and effects of cyclic peptidesTselios, T.; Daliani, I.; Probert, L.; Deraos, S.; Matsoukas, E.; Roy, S.; Pires, J.; Moore, G.; Matsoukas, J.
2000Treatment of experimental allergic encephalomyelitis (EAE) by a rationally designed cyclic analogue of myelin basic protein (MBP) epitope 72-85Tselios, T.; Daliani, I.; Deraos, S.; Thymianou, S.; Matsoukas, E.; Troganis, A.; Gerothanassis, I.; Mouzaki, A.; Mavromoustakos, Thomas; Probert, L.; Matsoukas, J.
1999The application of biophysical methods to study drug: membrane interactionsMavromoustakos, Thomas; Daliani, I.; Matsoukas, J.
1999Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffoldAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Smith, J.; Mavromoustakos, Thomas; Saifeddine, M.; Moore, G.; Hollenberg, M.; Matsoukas, J.
1999An effort to understand the molecular basis of hypertension through the study of conformational analysis of Losartan and Sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculationsMavromoustakos, Thomas; Kolocouris, A.; Zervou, Maria; Roumelioti, P.; Matsoukas, J.; Weisemann, R.
Showing results 1 to 20 of 28

 

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