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Showing results 1 to 20 of 93
DateTitleAuthor(s)
2002The 1.76 angstrom resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drugOikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Archontis, G.
19967-carbon mimics of D-glucose and L-fucose: Activation by 6R-, and inactivation by 6S, -6C-methylglucose of glycogen synthase: Inhibition of glucokinase and/or glucose-6-phosphataseBleriot, Y.; Smelt, K. H.; Cadefau, J.; Bollen, M.; Stalmans, W.; Biggadike, K.; Johnson, L. N.; Oikonomakos, Nikos G.; Lane, A. L.; Crook, S.; Watkin, D. J.; Fleet, G. W. J.
1996Activator anion binding site in pyridoxal phosphorylase b: The binding of phosphite, phosphate, and fluorophosphate in the crystalOikonomakos, Nikos G.; Zographos, Spyros E.; Tsitsanou, K. E.; Johnson, L. N.; Acharya, K. R.
2005Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetesKlabunde, T.; Wendt, K. U.; Kadereit, D.; Brachvogel, V.; Burger, H. J.; Herling, A. W.; Oikonomakos, Nikos G.; Kosmopoulou, M. N.; Schmoll, D.; Sarubbi, E.; von Roedern, E.; Schonafinger, K.; Defossa, E.
1999Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbox ylateOikonomakos, Nikos G.; Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Goldmann, S.; Bischoff, H.
1996alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptidesBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Cooper, R. I.; Watkin, D. J.; Oikonomakos, Nikos G.; Johnson, L. N.; Fleet, G. W. J.
1990The Ammonium-Sulfate Activation of Phosphorylase-BLeonidas, Demetres D.; Oikonomakos, Nikos G.; Papageorgiou, A. C.; Xenakis, Aristotelis; Cazianis, C.T.; Bem, F.
1995The Binding of 2-Deoxy-D-Glucose 6-Phosphate to Glycogen-Phosphorylase-B - Kinetic and Crystallographic StudiesOikonomakos, Nikos G.; Zographos, Spyros E.; Johnson, L. N.; Papageorgiou, A. C.; Acharya, K. R.
2006The binding of 3 '-N-piperidine-4-carboxyl-3 '-deoxy-ara-uridine to ribonuclease A in the crystalLeonidas, Demetres D.; Maiti, T. K.; Samanta, A.; Dasgupta, S.; Pathak, T.; Zographos, Spyros E.; Oikonomakos, Nikos G.
2003The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studiesPinotsis, N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Mavridis, I. M.
2005Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studiesChrysina, Evangelia D.; Kosmopoulou, M. N.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Kannan, T.; Loganathan, D.; Oikonomakos, Nikos G.
1989The Binding of Beta-Glycerophosphate to Glycogen Phosphorylase-B in the CrystalOikonomakos, Nikos G.; Acharya, K. R.; Melpidou, A. E.; Stuart, D. I.; Johnson, L. N.
1991The Binding of D-Gluconohydroximo-1,5-Lactone to Glycogen-Phosphorylase - Kinetic, Ultracentrifugation and Crystallographic StudiesPapageorgiou, A. C.; Oikonomakos, Nikos G.; Leonidas, Demetres D.; Bernet, B.; Beer, D.; Vasella, A.
2005The binding of IMP to ribonuclease AHatzopoulos, G. N.; Leonidas, Demetres D.; Kardakaris, R.; Kobe, J.; Oikonomakos, Nikos G.
2002Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b - Kinetic and crystallographic studiesOikonomakos, Nikos G.; Kosmopoulou, M.; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Somsak, U.; Nagy, V.; Praly, J. P.; Docsa, T.; Toth, A.; Gergely, P.
2006Binding of oxalyl derivatives of beta-D-glucopyranosylamine to muscle glycogen phosphorylase bHadjiloi, T.; Tiraidis, C.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Tsipos, P.; Gimisis, T.
2004Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b - Comparison with ligand binding to pCDK2-cyclin A complexKosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Bischler, N.; Eisenbrand, G.; Sakarellos, C. E.; Pauptit, R.; Oikonomakos, Nikos G.
2006Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside siteHampson, L. J.; Arden, C.; Agius, L.; Ganotidis, M.; Kosmopoulou, M. N.; Tiraidis, C.; Elemes, Y.; Sakarellos, C.; Leonidas, Demetres D.; Oikonomakos, Nikos G.
1996Characterisation, crystallisation and preliminary X-ray diffraction analysis of a Fab fragment of a rat monoclonal antibody with very high affinity for the human muscle acetylcholine receptorKontou, M.; Vatzaki, E. H.; Kokla, A.; Acharya, K. R.; Oikonomakos, Nikos G.; Tzartos, S. J.
1992Control of Phosphorylase-B Conformation by a Modified Cofactor - Crystallographic Studies on R-State Glycogen-Phosphorylase Reconstituted with Pyridoxal 5'-DiphosphateLeonidas, Demetres D.; Oikonomakos, Nikos G.; Papageorgiou, A. C.; Acharya, K. R.; Barford, D.; Johnson, L. N.
Showing results 1 to 20 of 93