Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	New‑onset neuropsychiatric sequelae and 'long‑COVID' syndrome (Review)
Δημιουργός/Συγγραφέας:	Efstathiou, Vasiliki Stefanou, Maria-Ioanna Demetriou, Marina Siafakas, Nikolaos Katsantoni, Eleni Makris, Michael Tsivgoulis, Georgios [EL] Ζουμπουρλής, Βασίλης[EN] Zoumpourlis, Vassilis Kympouropoulos, Stylianos Tsoporis, James N [EL] Σπαντίδος, Δημήτριος Α.[EN] Spandidos, Demetrios A. Ferentinos, Panagiotis Smyrnis, Nikolaos Rizos, Emmanouil
Ημερομηνία:	2022-11
ISSN:	1792-0981 1792-1015
DOI:	10.3892/etm.2022.11641
Άλλο:	36324612
Περίληψη:	The ongoing coronavirus disease 2019 (COVID-19) pandemic has had a widespread impact on individuals' mental health through indirect psychological and social mechanisms, related to factors such as fear of infection or death, social isolation, lack of social support and financial instability. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has also been associated with the development or recurrence of neuropsychiatric symptoms, both during the acute phase, as well as during the post-acute 'long-COVID' phase. In addition to the COVID-19 survivors with a mental health history that are at a high risk of experiencing a range of neuropsychiatric symptoms following resolution of acute COVID-19, there is accumulating evidence that a diagnosis of COVID-19 may also be associated with new-onset neuropsychiatric morbidity among survivors without pre-existing mental health disorders. In particular, studies investigating the incidence of post-acute neuropsychiatric sequelae, based mostly on retrospective cohort study designs and data from national health registries, have reported the development of new-onset manifestations, including depression, anxiety, psychotic symptoms, sleep disturbances and fatigue. Nevertheless, when COVID-19 survivors were compared with SARS-CoV-2-negative controls and especially survivors of other disorders (such as influenza), the findings regarding the risk of incident neuropsychiatric manifestations varied among studies. While there is evidence of an association between SARS-CoV-2 infection and the subsequent occurrence of new-onset neuropsychiatric symptoms, especially among patients with increased disease severity, further research using methodological approaches less susceptible to confounding bias is required to establish causal relationships.
Τίτλος πηγής δημοσίευσης:	Experimental and therapeutic medicine
Τόμος/Κεφάλαιο:	24
Τεύχος:	5
Θεματική Κατηγορία:	[EL] Επιδημίες. Επιδημιολογία[EN] Epidemics. Epidemiology [EL] Ιατρική-Δημόσια υγεία[EN] Medicine - public aspects [EL] Φυσιολογία[EN] Physiology [EL] Ιολογία[EN] Virology
Λέξεις-Κλειδιά:	COVID-19 COVID-19 survivors SARS-CoV-2 Incidence of neuropsychiatric symptoms Long‑COVID New‑onset neuropsychiatric manifestations Post‑COVID syndrome
Κάτοχος πνευματικών δικαιωμάτων:	© Efstathiou et al.
Όροι και προϋποθέσεις δικαιωμάτων:	This is an open access article distributed under the terms of Creative Commons Attribution License.
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://www.spandidos-publications.com/10.3892/etm.2022.11641
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο