|Title:||Synthesis, Structure and Antiproliferative Activity of Three Gallium(III) Azole Complexes|
Papaefstathiou, Giannis S.
Raptopoulou, Catherine C.
Papazisis, Konstantinos T.
Kortsaris, Alexandros H.
Zafiropoulos, Theodoros F.
|Type:||Journal Article (Scientific Journal article)|
|Abstract:||As part of our interest into the bioinorganic chemistry of gallium, gallium(III) complexes of the azole ligands 2,1,3-benzothiadiazole (btd), 1,2,3-benzotriazole (btaH) and 1- methyl-4,5-diphenylimidazole (L) have been isolated. Reaction of btaH or btd with GaBr3 or GaCl3 resulted in the mononuclear complexes [GaBr3(btaH)2] (1) and [GaCl3(btd)2] (2), respectively, while treatment of GaCl3 with L resulted in the anionic complex (LH)2[GaCl4]Cl (3). All three complexes were characterized by single-crystal X-ray crystallography and IR spectroscopy, while their antiproliferative activities were investigated against a series of human and mouse cancer cell lines.|
|Publisher:||Hindawi Publishing Corporation|
|Journal Title:||Bioinorganic Chemistry and Applications|
|Subject Category:||Science::Inorganic chemistry|
|Journal web Location :||http://www.hindawi.com/journals/bca/|
|Rights holder:||Copyright © 2010 Stergios Zanias et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.|
|Notes:||This is also freely available in PubMed Central at:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913727/|
|Source:||Bioinorganic Chemistry and Applications 2010(July2010):168030|
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