Αποτελέσματα 21 έως 40 από 66
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| Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 2003 | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 angstrom resolution | Oikonomakos, Nikos G.; Chrysina, Evangelia D.; Kosmopoulou, M. N.; Leonidas, Demetres D. | |
| 2003 | Crystallographic studies on alpha- and beta-D-glucopyranosyl formamide analogues, inhibitors of glycogen phosphorylase | Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Zographos, Spyros E.; Kosmopoulou, M. N.; Bischler, N.; Leonidas, Demetres D.; Kovacs, L.; Docsa, T.; Gergely, P.; Somsak, L. | |
| 2003 | The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies | Pinotsis, N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Mavridis, I. M. | |
| 2004 | Ορθολογιστικός σχεδιασμός νέων υπογλυκαιμικών φαρμάκων | Leonidas, Demetres D.; Chrysina, Evangelia D.; Κοσμοπούλου, Μάγδα Ν.; Καρδακάρη, Ροζίνα; Oikonomakos, Nikos G.; Bischler, Nicolas | |
| 2004 | Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b - Comparison with ligand binding to pCDK2-cyclin A complex | Kosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Bischler, N.; Eisenbrand, G.; Sakarellos, C. E.; Pauptit, R.; Oikonomakos, Nikos G. | |
| 2005 | The binding of IMP to ribonuclease A | Hatzopoulos, G. N.; Leonidas, Demetres D.; Kardakaris, R.; Kobe, J.; Oikonomakos, Nikos G. | |
| 2005 | Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies | Chrysina, Evangelia D.; Kosmopoulou, M. N.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Kannan, T.; Loganathan, D.; Oikonomakos, Nikos G. | |
| 2005 | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs | Oikonomakos, Nikos G.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Kostas, Ioannis D.; Wendt, K. U.; Klabunde, T.; Defossa, E. | |
| 2005 | Indirubin-3 '-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites | Kosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Eisenbrand, G.; Oikonomakos, Nikos G. | |
| 2005 | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site | Chrysina, Evangelia D.; Kosmopoulou, M. N.; Tiraidis, C.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Hadady, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Oikonomakos, Nikos G. | |
| 2006 | Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase | Anagnostou, E.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Hadjiloi, T.; Tiraidis, C.; Zographos, Spyros E.; Gyorgydeak, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Kolisis, Fragiskos N.; Oikonomakos, Nikos G. | |
| 2006 | Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site | Hampson, L. J.; Arden, C.; Agius, L.; Ganotidis, M.; Kosmopoulou, M. N.; Tiraidis, C.; Elemes, Y.; Sakarellos, C.; Leonidas, Demetres D.; Oikonomakos, Nikos G. | |
| 2006 | Binding of oxalyl derivatives of beta-D-glucopyranosylamine to muscle glycogen phosphorylase b | Hadjiloi, T.; Tiraidis, C.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Tsipos, P.; Gimisis, T. | |
| 2006 | The binding of 3 '-N-piperidine-4-carboxyl-3 '-deoxy-ara-uridine to ribonuclease A in the crystal | Leonidas, Demetres D.; Maiti, T. K.; Samanta, A.; Dasgupta, S.; Pathak, T.; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2006 | Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-beta-D-glucopyranosylamine | Petsalakis, E. I.; Chrysina, Evangelia D.; Tiraidis, C.; Hadjiloi, T.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Aich, U.; Varghese, B.; Loganathan, D. | |
| 2006 | Iminosugars as potential inhibitors of glycogenolysis: Structural insights into the molecular basis of glycogen phosphorylase inhibition | Oikonomakos, Nikos G.; Tiraidis, C.; Leonidas, Demetres D.; Zographos, Spyros E.; Kristiansen, M.; Jessen, C. U.; Norskov-Lauritsen, L.; Agius, L. | |
| 2006 | Indirubin and indigo analogues as potential inhibitors of glycogenolysis: structural basis of glycogen phosphorylase inhibition | Oikonomakos, Nikos G.; Kosmopoulou, Magda N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Tiraidis, Costas; Bischler, Nicolas; Tsitsanou, Katerina E.; Zographos, Spyros E.; Kostas, Ioannis D.; Eisenbrand, Gerhard | |
| 2007 | FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase | Tiraidis, C.; Alexacou, K. M.; Zographos, Spyros E.; Leonidas, Demetres D.; Gimisis, T.; Oikonomakos, Nikos G. | |
| 2007 | Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin | Leonidas, Demetres D.; Swamy, B. M.; Hatzopoulos, G. N.; Gonchigar, S. J.; Chachadi, V. B.; Inamdar, S. R.; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2007 | Recognition of ribonuclease a by 3 '-5 '-pyrophosphate-linked dinucleotide inhibitors: A molecular dynamics/continuum electrostatics analysis | Polydoridis, S.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Archontis, G. | |
