Αποτελέσματα 21 έως 40 από 68
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| Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 2002 | The 1.76 angstrom resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drug | Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Archontis, G. | |
| 2002 | Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b - Kinetic and crystallographic studies | Oikonomakos, Nikos G.; Kosmopoulou, M.; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Somsak, U.; Nagy, V.; Praly, J. P.; Docsa, T.; Toth, A.; Gergely, P. | |
| 2003 | Crystallographic studies on alpha- and beta-D-glucopyranosyl formamide analogues, inhibitors of glycogen phosphorylase | Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Zographos, Spyros E.; Kosmopoulou, M. N.; Bischler, N.; Leonidas, Demetres D.; Kovacs, L.; Docsa, T.; Gergely, P.; Somsak, L. | |
| 2005 | Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase | Watson, K. A.; Chrysina, Evangelia D.; Tsitsanou, K. E.; Zographos, Spyros E.; Archontis, G.; Fleet, G. W. J.; Oikonomakos, Nikos G. | |
| 2005 | Glycogen phosphorylase inhibitors: A free energy perturbation analysis of glucopyranose spirohydantoin analogues | Archontis, G.; Watson, K. A.; Xie, Q.; Andreou, G.; Chrysina, Evangelia D.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Karplus, M. | |
| 2006 | Iminosugars as potential inhibitors of glycogenolysis: Structural insights into the molecular basis of glycogen phosphorylase inhibition | Oikonomakos, Nikos G.; Tiraidis, C.; Leonidas, Demetres D.; Zographos, Spyros E.; Kristiansen, M.; Jessen, C. U.; Norskov-Lauritsen, L.; Agius, L. | |
| 2006 | The binding of 3 '-N-piperidine-4-carboxyl-3 '-deoxy-ara-uridine to ribonuclease A in the crystal | Leonidas, Demetres D.; Maiti, T. K.; Samanta, A.; Dasgupta, S.; Pathak, T.; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2006 | Indirubin and indigo analogues as potential inhibitors of glycogenolysis: structural basis of glycogen phosphorylase inhibition | Oikonomakos, Nikos G.; Kosmopoulou, Magda N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Tiraidis, Costas; Bischler, Nicolas; Tsitsanou, Katerina E.; Zographos, Spyros E.; Kostas, Ioannis D.; Eisenbrand, Gerhard | |
| 2006 | Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase | Anagnostou, E.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Hadjiloi, T.; Tiraidis, C.; Zographos, Spyros E.; Gyorgydeak, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Kolisis, Fragiskos N.; Oikonomakos, Nikos G. | |
| 2007 | FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase | Tiraidis, C.; Alexacou, K. M.; Zographos, Spyros E.; Leonidas, Demetres D.; Gimisis, T.; Oikonomakos, Nikos G. | |
| 2007 | Differential expression of molecular motors in the motor cortex of sporadic ALS | Pantelidou, M.; Zographos, Spyros E.; Lederer, C. W.; Kyriakides, T.; Pfaffl, M. W.; Santama, N. | |
| 2007 | Structural basis for the carbohydrate recognition of the Sclerotium rolfsii lectin | Leonidas, Demetres D.; Swamy, B. M.; Hatzopoulos, G. N.; Gonchigar, S. J.; Chachadi, V. B.; Inamdar, S. R.; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2008 | Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2, 3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N '-beta-D-glucopyranosyl urea binding | Alexacou, Kyra-Melinda; Hayes, Joseph M.; Tiraidis, Costas; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Archontis, Georgios; Oikonomakos, Nikos G.; Paul, Jashuva V.; Varghese, Babu; Loganathan, Duraikkannu | |
| 2008 | Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: Synthesis, structure-activity relationships, and X-ray crystallographic studies | Wen, Xiaoan; Sun, Hongbin; Liu, Jun; Cheng, Keguang; Zhang, Pu; Zhang, Liying; Hao, Jia; Zhang, Luyong; Ni, Peizhou; Zographos, Spyros E.; Leonidas, Demetres D.; Alexacou, Kyra-Melinda; Gimisis, Thanasis; Hayes, Joseph M.; Oikonomakos, Nikos G. | |
| 2008 | Pentacyclic triterpenes, inhibitors of glycogen phosphorylase, as potential drugs for type 2 diabetes: X-ray crystallographic studies | Zographos, Spyros E.; Leonidas, Demetres D.; Alexacou, K. M.; Gimisis, T.; Hayes, J. M.; Oikonomakos, Nikos G.; Wen, X.; Sun, H.; Liu, J.; Cheng, K.; Zhang, P.; Zhang, L.; Hao, J.; Zhang, L.; Ni, P. | |
| 2008 | New Inhibitors of Glycogen Phosphorylase as Potential Antidiabetic Agents | Somsak, L.; Czifrak, K.; Toth, M.; Bokor, E.; Chrysina, Evangelia D.; Alexacou, K. -M.; Hayes, J. M.; Tiraidis, C.; Lazoura, E.; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2009 | Morpholino, Piperidino, and Pyrrolidino Derivatives of Pyrimidine Nucleosides as Inhibitors of Ribonuclease A: Synthesis, Biochemical, and Crystallographic Evaluation | Samanta, Anirban; Leonidas, Demetres D.; Dasgupta, Swagata; Pathak, Tanmaya; Zographos, Spyros E.; Oikonomakos, Nikos G. | |
| 2009 | Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case | Chrysina, Evangelia D.; Bokor, Eva; Alexacou, Kyra-Melinda; Charavgi, Maria-Despoina; Oikonomakos, George N.; Zographos, Spyros E.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Laszlo, Somsak | |
| 2009 | Inhibitor design for ribonuclease A: the binding of two 5 '-phosphate uridine analogues | Tsirkone, Vicky G.; Dossi, Kyriaki; Drakou, Christina; Zographos, Spyros E.; Kontou, Maria; Leonidas, Demetres D. | |
| 2009 | Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors | Benltifa, Mahmoud; Hayes, Joseph M.; Vidal, Sebastien; Gueyrard, David; Goekjian, Peter G.; Praly, Jean-Pierre; Kizilis, Gregory; Tiraidis, Costas; Alexacou, Kyra-Melinda; Chrysina, Evangelia D.; Zographos, Spyros E.; Leonidas, Demetres D.; Archontis, Georgios; Oikonomakos, Nikos G. | |
