Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 2003 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors | Leonidas, Demetres D.; Chavali, G. B.; Oikonomakos, Nikos G.; Chrysina, Evangelia D.; Kosmopoulou, M. N.; Vlassi, M.; Frankling, C.; Acharya, K. R. | |
| 2003 | Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 angstrom resolution | Oikonomakos, Nikos G.; Chrysina, Evangelia D.; Kosmopoulou, M. N.; Leonidas, Demetres D. | |
| 2003 | Crystallographic studies on alpha- and beta-D-glucopyranosyl formamide analogues, inhibitors of glycogen phosphorylase | Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Zographos, Spyros E.; Kosmopoulou, M. N.; Bischler, N.; Leonidas, Demetres D.; Kovacs, L.; Docsa, T.; Gergely, P.; Somsak, L. | |
| 2003 | Crystallization and preliminary X-ray crystallographic analysis of Sclerotium rolfsii lectin | Leonidas, Demetres D.; Swamy, B. M.; Bhat, A. G.; Inamdar, S. R.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Oikonomakos, Nikos G. | |
| 2004 | Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b - Comparison with ligand binding to pCDK2-cyclin A complex | Kosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Bischler, N.; Eisenbrand, G.; Sakarellos, C. E.; Pauptit, R.; Oikonomakos, Nikos G. | |
| 2005 | Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes | Klabunde, T.; Wendt, K. U.; Kadereit, D.; Brachvogel, V.; Burger, H. J.; Herling, A. W.; Oikonomakos, Nikos G.; Kosmopoulou, M. N.; Schmoll, D.; Sarubbi, E.; von Roedern, E.; Schonafinger, K.; Defossa, E. | |
| 2005 | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site | Chrysina, Evangelia D.; Kosmopoulou, M. N.; Tiraidis, C.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Hadady, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Oikonomakos, Nikos G. | |
| 2005 | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs | Oikonomakos, Nikos G.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Kostas, Ioannis D.; Wendt, K. U.; Klabunde, T.; Defossa, E. | |
| 2005 | Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies | Chrysina, Evangelia D.; Kosmopoulou, M. N.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Kannan, T.; Loganathan, D.; Oikonomakos, Nikos G. | |
| 2005 | Indirubin-3 '-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites | Kosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Eisenbrand, G.; Oikonomakos, Nikos G. | |
| 2006 | Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site | Hampson, L. J.; Arden, C.; Agius, L.; Ganotidis, M.; Kosmopoulou, M. N.; Tiraidis, C.; Elemes, Y.; Sakarellos, C.; Leonidas, Demetres D.; Oikonomakos, Nikos G. | |
| 2006 | Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase | Anagnostou, E.; Kosmopoulou, M. N.; Chrysina, Evangelia D.; Leonidas, Demetres D.; Hadjiloi, T.; Tiraidis, C.; Zographos, Spyros E.; Gyorgydeak, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Kolisis, Fragiskos N.; Oikonomakos, Nikos G. | |