@article{Yu Y._Zhang K.-D._ Petsalakis I.D._ Theodorakopoulos G._Rebek J._Jr._2018, title={Asymmetric binding of symmetric guests in a water-soluble cavitand}, volume={30}, ISSN={1061-0278}, archiveLocation={Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο}, url={https://hdl.handle.net/10442/16862}, DOI={10.1080/10610278.2017.1422868}, abstractNote={Binding of long aliphatic chains in water-soluble container compounds is driven by the hydrophobic effect: the CH2 groups of the guests are buried from water and solvate the inner aromatic surface of the host. The hydrophobic forces and the CH-π attractions are often sufficient to contort the guests into otherwise unfavorable shapes. Here we show that alkanes, α,ω-diols, α,ω-diacids and their methyl esters assume folded, J-shaped conformations in a water-soluble cavitand. The environment of the guest’s ends interconvert rapidly on the NMR timescale through yo-yo like motions. The applications of water-soluble cavitands to reaction processes are discussed in the context of moving vs. fixed guest ends.}, number={5–6}, journal={Supramolecular Chemistry}, publisher={Taylor and Francis Ltd.}, author={Yu Y. and Zhang K.-D. and Petsalakis I.D. and Theodorakopoulos G. and Rebek J. and Jr.}, year={2018}, pages={473–478} }