@article{Vlassi E._ Papagiannopoulos A._ Pispas S._2017, title={Amphiphilic poly(2-oxazoline) copolymers as self-assembled carriers for drug delivery applications}, volume={88}, ISSN={0014-3057}, archiveLocation={Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο}, url={https://hdl.handle.net/10442/16943}, DOI={10.1016/j.eurpolymj.2016.10.034}, abstractNote={The potential of poly(2-oxazoline) containing copolymers for drug delivery is discussed in this feature article. Advances in synthetic routes for 2-oxazoline copolymerization and chemical modification of biocompatible poly(2-oxazoline) copolymers allow the control of amphiphilic poly(2-oxazoline) copolymers at the molecular level. Thus macromolecular design dictates self-organization of poly(2-oxazoline) copolymers at the nano-scale into morphologically diverse, functional nanostructures in aqueous solutions, able to respond to changes caused by external stimuli and showing fine-tuned interactions, loading and release properties of encapsulated hydrophobic drugs and biological macromolecules. The latest advances in the use of poly(2-oxazoline) containing copolymers as carriers of hydrophobic drugs, therapeutic proteins/peptides and nucleic acids are presented through representative examples from recent literature. It can be safely concluded that nanocarriers based on poly(2-oxazoline) containing block copolymers show a great potential for applications in the biomedical field in the near future.}, journal={European Polymer Journal}, publisher={Elsevier Ltd}, author={Vlassi E. and Papagiannopoulos A. and Pispas S.}, year={2017}, pages={516–523} }