%0 Journal Article %A Halabalaki, Maria%A %A Alexi, Xanthippi%A %A Aligiannis, Necktarios%A %A Alexis, Michael N.%A %A Skaltsounis, Alexios-Leandros %D 2008 %T Ebenfurans IV-VIII from Onobrychis ebenoides: Evidence that C-Prenylation is the Key Determinant of the Cytotoxicity of 3-Formyl-2-arylbenzofurans %J Journal of Natural Products %V 71 %@ 0163-3864 %R 10.1021/np800134h %I American Chemical Society %P 1934–1937 %N 11 %U https://hdl.handle.net/10442/12208 %X Phytochemical investigation of a methanol extract of Onobrychis ebenoides yielded five new 3-formyl-2-arylbenzofurans, namely, ebenfurans IV-VII (1-5), together with the known compounds ebenfurans I, II (6), and III (7). Only 1 and 7 exhibited growth inhibitory activity against MCF-7 and Ishikawa cells, suggesting that the prenyl moiety at position C-5 is the key determinant of the cytotoxic activity of this group of compounds. %> Αποθετήριο Ήλιος / ΕΙΕ