Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Effects of rich in Β-glucans edible mushrooms on aging gut microbiota characteristics: An in vitro study
Δημιουργός/Συγγραφέας:	Mitsou, Evdokia K Saxami, Georgia Stamoulou, Emmanuela Kerezoudi, Evangelia Terzi, Eirini Koutrotsios, Georgios Bekiaris, Georgios Zervakis, Georgios I Mountzouris, Konstantinos C [EL] Πλέτσα, Βασιλική[EN] Pletsa, Vassiliki Kyriacou, Adamantini
Ημερομηνία:	2020-06-18
Γλώσσα:	Αγγλικά
ISSN:	1420-3049
DOI:	10.3390/molecules25122806
Άλλο:	32570735
Περίληψη:	Alterations of gut microbiota are evident during the aging process. Prebiotics may restore the gut microbial balance, with β-glucans emerging as prebiotic candidates. This study aimed to investigate the impact of edible mushrooms rich in β-glucans on the gut microbiota composition and metabolites by using in vitro static batch culture fermentations and fecal inocula from elderly donors (n = 8). Pleurotus ostreatus, P. eryngii, Hericium erinaceus and Cyclocybe cylindracea mushrooms derived from various substrates were examined. Gut microbiota composition (quantitative PCR (qPCR)) and short-chain fatty acids (SCFAs; gas chromatography (GC)) were determined during the 24-h fermentation. P. eryngii induced a strong lactogenic effect, while P. ostreatus and C. cylindracea induced a significant bifidogenic effect (p for all <0.05). Furthermore, P. eryngii produced on wheat straw and the prebiotic inulin had comparable Prebiotic Indexes, while P. eryngii produced on wheat straw/grape marc significantly increased the levels of tested butyrate producers. P. ostreatus, P. eryngii and C. cylindracea had similar trends in SCFA profile; H. erinaceus mushrooms were more diverse, especially in the production of propionate, butyrate and branched SCFAs. In conclusion, mushrooms rich in β-glucans may exert beneficial in vitro effects in gut microbiota and/or SCFAs production in elderly subjects.
Τίτλος πηγής δημοσίευσης:	Molecules (Basel, Switzerland)
Τόμος/Κεφάλαιο:	25
Τεύχος:	12
Σελίδες:	2806
Θεματική Κατηγορία:	[EL] Φαρμακευτική χημεία[EN] Pharmaceutical chemistry [EL] Ιατρική[EN] Medicine [EL] Βιοτεχνολογία[EN] Biotechnology
Λέξεις-Κλειδιά:	Cyclocybe cylindracea Hericium erinaceus Pleurotus eryngii Pleurotus ostreatus SCFAs Aging Edible mushrooms Gut microbiota Prebiotic β-glucans Aged Female Humans Male Beta - Glucans Agaricales Gastrointestinal Microbiome
Κάτοχος πνευματικών δικαιωμάτων:	Copyright © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://www.mdpi.com/1420-3049/25/12/2806
Ηλεκτρονική διεύθυνση περιοδικού (link) :	https://www.mdpi.com/journal/molecules
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο