Αποτελέσματα 9 έως 28 από 28
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Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 1994 | Molecular modeling on non-peptide ANG II receptor antagonist | Mavromoustakos, Thomas; Theodoropoulou, E.; Matsoukas, J.; Moore, G.; Smith, J. | |
| 2004 | Hematocrit-lowering effect following inactivation of renin-angiotensin system with angiotensin converting enzyme inhibitors and angiotensin receptor blockers | Marathias, K. P.; Agroyannis, B.; Mavromoustakos, Thomas; Matsoukas, J.; Vlahakos, D. V. | |
| 1999 | An effort to understand the molecular basis of hypertension through the study of conformational analysis of Losartan and Sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculations | Mavromoustakos, Thomas; Kolocouris, A.; Zervou, Maria; Roumelioti, P.; Matsoukas, J.; Weisemann, R. | |
| 2006 | Design, synthesis, and molecular modeling of a novel amide-linked cyclic GnRH analogue cyclo(4-9)[Lys(4),D-Trp(6),Glu(9)]GnRH: Stimulation of gonadotropin gene expression | Keramida, M. K.; Tselios, T.; Mantzourani, E.; Papazisis, K.; Mavromoustakos, Thomas; Klaussen, C.; Agelis, G.; Deraos, S.; Friligou, I.; Habibi, H.; Matsoukas, J. | |
| 2001 | Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence with fixed conformations of pharmacophoric groups: Importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimetics | Alexopoulos, K.; Panagiotopoulos, D.; Mavromoustakos, Thomas; Fatseas, P.; Paredes-Carbajal, M. C.; Mascher, D.; Mihailescu, S.; Matsoukas, J. | |
| 2002 | Design, synthesis and biological evaluation of cyclic Angiotensin II analogues with 3,5 side-chain bridges: Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists | Roumelioti, P.; Polevaya, L.; Zoumpoulakis, Panagiotis; Giatas, N.; Mutule, I.; Keivish, T.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Kremastinos, D.; Grdadolnik, S. G.; Mavromoustakos, Thomas; Matsoukas, J. | |
| 2003 | Design, conformation and bioactivity of novel angiotensin II receptor antagonists | Mavromoustakos, Thomas; Zoumpoulakis, Panagiotis; Roumelioti, P.; Giatas, N.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Matsoukas, J. | |
| 1999 | Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffold | Alexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Smith, J.; Mavromoustakos, Thomas; Saifeddine, M.; Moore, G.; Hollenberg, M.; Matsoukas, J. | |
| 2004 | Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence: Platelet aggregation and relaxant activities | Alexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Roumelioti, P.; Mavromoustakos, Thomas; Mihailescu, S.; Paredes-Carbajal, M. C.; Mascher, D.; Matsoukas, J. | |
| 2005 | Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: Enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators | Matsoukas, J.; Apostolopoulos, V.; Kalbacher, H.; Papini, A. M.; Tselios, T.; Chatzantoni, K.; Biagioli, T.; Lolli, F.; Deraos, S.; Papathanassopoulos, P.; Troganis, A.; Mantzourani, E.; Mavromoustakos, Thomas; Mouzaki, A. | |
| 1997 | Conformational properties of the immunomodulator linomide | Mavromoustakos, Thomas; Theodoropoulou, E.; Zervou, Maria; Karussis, D.; Matsoukas, J. | |
| 1997 | Conformational analysis of the thrombin receptor agonist peptides SFLLR and SFLLR-NH2 by NMR: Evidence for a cyclic bioactive conformation | Matsoukas, J.; Hollenberg, M. D.; Mavromoustakos, Thomas; Panagiotopoulos, D.; Alexopulos, K.; Yamdagni, R.; Wu, Q.; Moore, G. J. | |
| 2003 | Conformation and bioactivity: design and discovery of novel antihypertensive drugs | Mavromoustakos, Thomas; Zervou, Maria; Zoumpoulakis, Panagiotis; Kyrikou, I.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P.M.; Kamoutsis, C.; Dimitriou, D.; Pitsas, A.; Matsoukas, J. | |
| 2004 | Conformation and bioactivity. Design and discovery of novel antihypertensive drugs | Mavromoustakos, Thomas; Zervou, Maria; Zoumpoulakis, Panagiotis; Kyrikou, I.; Benetis, N. P.; Polevaya, L.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P. M.; Kolocouris, A.; Vlahakos, D.; Grdadolnik, S. G.; Matsoukas, J. | |
| 1998 | A comparative SAR study of thrombin receptor derived non peptide mimetics: Importance of phenyl/guanidino proximity for activity | Alexopoulos, K.; Matsoukas, J.; Tselios, T.; Roumelioti, P.; Mavromoustakos, Thomas; Holada, K. | |
| 1998 | A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity | Alexopoulos, K.; Matsoukas, J.; Tselios, T.; Roumelioti, P.; Mavromoustakos, Thomas; Holada, K. | |
| 2002 | Applications of peptide mimetics in cancer | Apostolopoulos, V.; Matsoukas, J.; Plebanski, A.; Mavromoustakos, Thomas | |
| 1999 | The application of biophysical methods to study drug: membrane interactions | Mavromoustakos, Thomas; Daliani, I.; Matsoukas, J. | |
| 2001 | Antihypertensive drugs that act on Renin-Angiotensin System with emphasis in AT(1) antagonists | Mavromoustakos, Thomas; Apostolopoulos, V.; Matsoukas, J. | |
| 2002 | Antagonistic effects of human cyclic MBP87-99 altered peptide ligands in experimental allergic encephalomyelitis and human T-cell proliferation | Tselios, T.; Apostolopoulos, V.; Daliani, I.; Deraos, S.; Grdadolnik, S.; Mavromoustakos, Thomas; Melachrinou, M.; Thymianou, S.; Probert, L.; Mouzaki, A.; Matsoukas, J. | |