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DateTitleAuthor(s)Full text
2004Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence: Platelet aggregation and relaxant activitiesAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Roumelioti, P.; Mavromoustakos, Thomas; Mihailescu, S.; Paredes-Carbajal, M. C.; Mascher, D.; Matsoukas, J.
2004Conformation and bioactivity. Design and discovery of novel antihypertensive drugsMavromoustakos, Thomas; Zervou, Maria; Zoumpoulakis, Panagiotis; Kyrikou, I.; Benetis, N. P.; Polevaya, L.; Roumelioti, P.; Giatas, N.; Zoga, A.; Minakakis, P. M.; Kolocouris, A.; Vlahakos, D.; Grdadolnik, S. G.; Matsoukas, J.
2003Design, conformation and bioactivity of novel angiotensin II receptor antagonistsMavromoustakos, Thomas; Zoumpoulakis, Panagiotis; Roumelioti, P.; Giatas, N.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Matsoukas, J.
2003Conformational and biological studies for a pair of novel synthetic AT(1) antagonists: stereoelectronic requirements for antihypertensive efficacyZoumpoulakis, Panagiotis; Zoga, A.; Roumelioti, P.; Giatas, N.; Grdadolnik, S. G.; Iliodromitis, E.; Vlahakos, D.; Kremastinos, D.; Matsoukas, J. M.; Mavromoustakos, Thomas
2002Design, synthesis and biological evaluation of cyclic Angiotensin II analogues with 3,5 side-chain bridges: Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonistsRoumelioti, P.; Polevaya, L.; Zoumpoulakis, Panagiotis; Giatas, N.; Mutule, I.; Keivish, T.; Zoga, A.; Vlahakos, D.; Iliodromitis, E.; Kremastinos, D.; Grdadolnik, S. G.; Mavromoustakos, Thomas; Matsoukas, J.
1999Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffoldAlexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Smith, J.; Mavromoustakos, Thomas; Saifeddine, M.; Moore, G.; Hollenberg, M.; Matsoukas, J.
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