Αποτελέσματα 1 έως 8 από 8
Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 1996 | Synthesis and activities of cyclic thrombin-receptor-derived peptide analogues of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence containing D-Phe and/or D-Arg | Panagiotopoulos, D.; Matsoukas, J. M.; Alexopoulos, K.; Zebeki, A.; Μαυρομούστακος, Θωμάς; Saifeddine, M.; Hollenberg, M. D. | |
| 1997 | Use of molecular modeling to study superimposition of the thrombin receptor motif S42FLLR46 with its peptidomimetic analogs | Μαυρομούστακος, Θωμάς; Theodoropoulou, E.; Alexopoulos, K.; Matsoukas, J.; Hollenberg, M.; Moore, G. J. | |
| 1998 | A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity | Alexopoulos, K.; Matsoukas, J.; Tselios, T.; Roumelioti, P.; Μαυρομούστακος, Θωμάς; Holada, K. | |
| 1998 | A comparative SAR study of thrombin receptor derived non peptide mimetics: Importance of phenyl/guanidino proximity for activity | Alexopoulos, K.; Matsoukas, J.; Tselios, T.; Roumelioti, P.; Μαυρομούστακος, Θωμάς; Holada, K. | |
| 1999 | Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffold | Alexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Smith, J.; Μαυρομούστακος, Θωμάς; Saifeddine, M.; Moore, G.; Hollenberg, M.; Matsoukas, J. | |
| 2000 | Structural comparison between type I and type II antagonists: Possible implications in the drug design of AT1 antagonists | Roumelioti, P.; Tselios, T.; Alexopoulos, K.; Μαυρομούστακος, Θωμάς; Kolocouris, A.; Moore, G. J.; Matsoukas, J. M. | |
| 2001 | Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence with fixed conformations of pharmacophoric groups: Importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimetics | Alexopoulos, K.; Panagiotopoulos, D.; Μαυρομούστακος, Θωμάς; Fatseas, P.; Paredes-Carbajal, M. C.; Mascher, D.; Mihailescu, S.; Matsoukas, J. | |
| 2004 | Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser(42)-Phe-Leu-Leu-Arg(46) motif sequence: Platelet aggregation and relaxant activities | Alexopoulos, K.; Fatseas, P.; Melissari, E.; Vlahakos, D.; Roumelioti, P.; Μαυρομούστακος, Θωμάς; Mihailescu, S.; Paredes-Carbajal, M. C.; Mascher, D.; Matsoukas, J. | |