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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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1985Crystallization of Pig Skeletal Phosphorylase-B - Purification, Physical and Catalytic CharacterizationOikonomakos, Nikos G.; Melpidou, A. E.; Johnson, L. N.
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1988Uridine(5')Diphospho(1)-Alpha-D-Glucose - a Binding Study to Glycogen Phosphorylase-B in the CrystalOikonomakos, Nikos G.; Acharya, K. R.; Stuart, D. I.; Melpidou, A. E.; McLaughlin, P. J.; Johnson, L. N.
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1989X-ray diffraction studies on enzyme catalysis and allosteric control of glycogen phosphorylase bOikonomakos, Nikos G.; Acharya, K. R.; Johnson, L. N.; Papageorgiou, A. C.; Leonidas, Demetres D.
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1989The Binding of Beta-Glycerophosphate to Glycogen Phosphorylase-B in the CrystalOikonomakos, Nikos G.; Acharya, K. R.; Melpidou, A. E.; Stuart, D. I.; Johnson, L. N.
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1992Control of Phosphorylase-B Conformation by a Modified Cofactor - Crystallographic Studies on R-State Glycogen-Phosphorylase Reconstituted with Pyridoxal 5'-DiphosphateLeonidas, Demetres D.; Oikonomakos, Nikos G.; Papageorgiou, A. C.; Acharya, K. R.; Barford, D.; Johnson, L. N.
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1993X-Ray Crystallographic Analysis of 2,6-Anhydro-N-Methyl-D-Glycero-D-Ido-Heptonamide - the 1st Example of a Simple Glucose Analog with a Skew Boat StructureWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Ford, P.; Watkin, D. J.; Oikonomakos, Nikos G.
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1994The Design of Potential Antidiabetic Drugs - Experimental Investigation of a Number of Beta-D-Glucose Analog Inhibitors of Glycogen-PhosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
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1994The design of potential antidiabetic drugs: Experimental investigation of a number of ?-D-glucose analogue inhibitors of glycogen phosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
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1995Sulfate-Activated Phosphorylase-B - the Ph-Dependence of Catalytic ActivityZographos, Spyros E.; Oikonomakos, Nikos G.; Dixon, H. B. F.; Griffin, W. G.; Johnson, L. N.; Leonidas, Demetres D.
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1995Specific-Inhibition of Glycogen-Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of GlucopyranoseKrulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Crook, S.; Watkin, D. J.; Griffiths, R. C.; Nash, R. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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1995N-Acetyl-Beta-D-Glucopyranosylamine - a Potent T-State Inhibitor of Glycogen-Phosphorylase - a Comparison with Alpha-D-GlucoseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Watson, K. A.; Johnson, L. N.; Bichard, C. J. F.; Fleet, G. W. J.; Acharya, K. R.
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1995Spirohydantoins of Glucofuranose - Analogs of HydantocidinBrandstetter, T. W.; Kim, Y. H.; Son, J. C.; Taylor, H. M.; Lilley, P. M. D.; Watkin, D. J.; Johnson, L. N.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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1995The Binding of 2-Deoxy-D-Glucose 6-Phosphate to Glycogen-Phosphorylase-B - Kinetic and Crystallographic StudiesOikonomakos, Nikos G.; Zographos, Spyros E.; Johnson, L. N.; Papageorgiou, A. C.; Acharya, K. R.
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1995Glucose Analog Inhibitors of Glycogen-Phosphorylase - from Crystallographic Analysis to Drug Prediction Using Grid Force-Field and Golpe Variable SelectionWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Cruciani, G.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Oikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.
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1995Potent Inhibition of Glycogen-Phosphorylase by a Spirohydantoin of Glucopyranose - First Pyranose Analogs of HydantocidinBichard, C. J. F.; Mitchell, E. P.; Wormald, M. R.; Watson, K. A.; Johnson, L. N.; Zographos, Spyros E.; Koutra, D. D.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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1996alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptidesBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Cooper, R. I.; Watkin, D. J.; Oikonomakos, Nikos G.; Johnson, L. N.; Fleet, G. W. J.
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19967-carbon mimics of D-glucose and L-fucose: Activation by 6R-, and inactivation by 6S, -6C-methylglucose of glycogen synthase: Inhibition of glucokinase and/or glucose-6-phosphataseBleriot, Y.; Smelt, K. H.; Cadefau, J.; Bollen, M.; Stalmans, W.; Biggadike, K.; Johnson, L. N.; Oikonomakos, Nikos G.; Lane, A. L.; Crook, S.; Watkin, D. J.; Fleet, G. W. J.
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1996Activator anion binding site in pyridoxal phosphorylase b: The binding of phosphite, phosphate, and fluorophosphate in the crystalOikonomakos, Nikos G.; Zographos, Spyros E.; Tsitsanou, K. E.; Johnson, L. N.; Acharya, K. R.
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1996Glucofuranose analogues of hydantocidinBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Johnson, L. N.; Crook, S.; Lilley, Pmdq; Watkin, D. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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1997Stereospecific synthesis of spirohydantoins of beta-glucopyranose: Inhibitors of glycogen phosphorylaseKrulle, T. M.; delaFuente, C.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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