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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
1985Crystallization of Pig Skeletal Phosphorylase-B - Purification, Physical and Catalytic CharacterizationΟικονομάκος, Νίκος Γ.; Melpidou, A. E.; Johnson, L. N.
1988Uridine(5')Diphospho(1)-Alpha-D-Glucose - a Binding Study to Glycogen Phosphorylase-B in the CrystalΟικονομάκος, Νίκος Γ.; Acharya, K. R.; Stuart, D. I.; Melpidou, A. E.; McLaughlin, P. J.; Johnson, L. N.
1989X-ray diffraction studies on enzyme catalysis and allosteric control of glycogen phosphorylase bΟικονομάκος, Νίκος Γ.; Acharya, K. R.; Johnson, L. N.; Papageorgiou, A. C.; Λεωνίδας, Δημήτρης Δ.
1989The Binding of Beta-Glycerophosphate to Glycogen Phosphorylase-B in the CrystalΟικονομάκος, Νίκος Γ.; Acharya, K. R.; Melpidou, A. E.; Stuart, D. I.; Johnson, L. N.
1992Control of Phosphorylase-B Conformation by a Modified Cofactor - Crystallographic Studies on R-State Glycogen-Phosphorylase Reconstituted with Pyridoxal 5'-DiphosphateΛεωνίδας, Δημήτρης Δ.; Οικονομάκος, Νίκος Γ.; Papageorgiou, A. C.; Acharya, K. R.; Barford, D.; Johnson, L. N.
1993X-Ray Crystallographic Analysis of 2,6-Anhydro-N-Methyl-D-Glycero-D-Ido-Heptonamide - the 1st Example of a Simple Glucose Analog with a Skew Boat StructureWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Ford, P.; Watkin, D. J.; Οικονομάκος, Νίκος Γ.
1994The design of potential antidiabetic drugs: Experimental investigation of a number of ?-D-glucose analogue inhibitors of glycogen phosphorylaseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Λεωνίδας, Δημήτρης Δ.; Acharya, K. R.
1994The Design of Potential Antidiabetic Drugs - Experimental Investigation of a Number of Beta-D-Glucose Analog Inhibitors of Glycogen-PhosphorylaseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Λεωνίδας, Δημήτρης Δ.; Acharya, K. R.
1995The Binding of 2-Deoxy-D-Glucose 6-Phosphate to Glycogen-Phosphorylase-B - Kinetic and Crystallographic StudiesΟικονομάκος, Νίκος Γ.; Ζωγράφος, Σπύρος Ε.; Johnson, L. N.; Papageorgiou, A. C.; Acharya, K. R.
1995Glucose Analog Inhibitors of Glycogen-Phosphorylase - from Crystallographic Analysis to Drug Prediction Using Grid Force-Field and Golpe Variable SelectionWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Cruciani, G.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Οικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.
1995Specific-Inhibition of Glycogen-Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of GlucopyranoseKrulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Crook, S.; Watkin, D. J.; Griffiths, R. C.; Nash, R. J.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
1995Sulfate-Activated Phosphorylase-B - the Ph-Dependence of Catalytic ActivityΖωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Dixon, H. B. F.; Griffin, W. G.; Johnson, L. N.; Λεωνίδας, Δημήτρης Δ.
1995Spirohydantoins of Glucofuranose - Analogs of HydantocidinBrandstetter, T. W.; Kim, Y. H.; Son, J. C.; Taylor, H. M.; Lilley, P. M. D.; Watkin, D. J.; Johnson, L. N.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
1995N-Acetyl-Beta-D-Glucopyranosylamine - a Potent T-State Inhibitor of Glycogen-Phosphorylase - a Comparison with Alpha-D-GlucoseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Watson, K. A.; Johnson, L. N.; Bichard, C. J. F.; Fleet, G. W. J.; Acharya, K. R.
1995Potent Inhibition of Glycogen-Phosphorylase by a Spirohydantoin of Glucopyranose - First Pyranose Analogs of HydantocidinBichard, C. J. F.; Mitchell, E. P.; Wormald, M. R.; Watson, K. A.; Johnson, L. N.; Ζωγράφος, Σπύρος Ε.; Koutra, D. D.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
19967-carbon mimics of D-glucose and L-fucose: Activation by 6R-, and inactivation by 6S, -6C-methylglucose of glycogen synthase: Inhibition of glucokinase and/or glucose-6-phosphataseBleriot, Y.; Smelt, K. H.; Cadefau, J.; Bollen, M.; Stalmans, W.; Biggadike, K.; Johnson, L. N.; Οικονομάκος, Νίκος Γ.; Lane, A. L.; Crook, S.; Watkin, D. J.; Fleet, G. W. J.
1996alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptidesBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Cooper, R. I.; Watkin, D. J.; Οικονομάκος, Νίκος Γ.; Johnson, L. N.; Fleet, G. W. J.
1996Activator anion binding site in pyridoxal phosphorylase b: The binding of phosphite, phosphate, and fluorophosphate in the crystalΟικονομάκος, Νίκος Γ.; Ζωγράφος, Σπύρος Ε.; Tsitsanou, K. E.; Johnson, L. N.; Acharya, K. R.
1996Glucofuranose analogues of hydantocidinBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Johnson, L. N.; Crook, S.; Lilley, Pmdq; Watkin, D. J.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Χρυσίνα, Ευαγγελία Δ.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
1997Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylasedelaFuente, C.; Krulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.