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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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1994The Design of Potential Antidiabetic Drugs - Experimental Investigation of a Number of Beta-D-Glucose Analog Inhibitors of Glycogen-PhosphorylaseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Λεωνίδας, Δημήτρης Δ.; Acharya, K. R.
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1994The design of potential antidiabetic drugs: Experimental investigation of a number of ?-D-glucose analogue inhibitors of glycogen phosphorylaseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Λεωνίδας, Δημήτρης Δ.; Acharya, K. R.
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1995Glucose Analog Inhibitors of Glycogen-Phosphorylase - from Crystallographic Analysis to Drug Prediction Using Grid Force-Field and Golpe Variable SelectionWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Cruciani, G.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Οικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.
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1995Potent Inhibition of Glycogen-Phosphorylase by a Spirohydantoin of Glucopyranose - First Pyranose Analogs of HydantocidinBichard, C. J. F.; Mitchell, E. P.; Wormald, M. R.; Watson, K. A.; Johnson, L. N.; Ζωγράφος, Σπύρος Ε.; Koutra, D. D.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1995Specific-Inhibition of Glycogen-Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of GlucopyranoseKrulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Crook, S.; Watkin, D. J.; Griffiths, R. C.; Nash, R. J.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1995The Binding of 2-Deoxy-D-Glucose 6-Phosphate to Glycogen-Phosphorylase-B - Kinetic and Crystallographic StudiesΟικονομάκος, Νίκος Γ.; Ζωγράφος, Σπύρος Ε.; Johnson, L. N.; Papageorgiou, A. C.; Acharya, K. R.
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1995Sulfate-Activated Phosphorylase-B - the Ph-Dependence of Catalytic ActivityΖωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Dixon, H. B. F.; Griffin, W. G.; Johnson, L. N.; Λεωνίδας, Δημήτρης Δ.
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1995N-Acetyl-Beta-D-Glucopyranosylamine - a Potent T-State Inhibitor of Glycogen-Phosphorylase - a Comparison with Alpha-D-GlucoseΟικονομάκος, Νίκος Γ.; Kontou, M.; Ζωγράφος, Σπύρος Ε.; Watson, K. A.; Johnson, L. N.; Bichard, C. J. F.; Fleet, G. W. J.; Acharya, K. R.
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1996Activator anion binding site in pyridoxal phosphorylase b: The binding of phosphite, phosphate, and fluorophosphate in the crystalΟικονομάκος, Νίκος Γ.; Ζωγράφος, Σπύρος Ε.; Tsitsanou, K. E.; Johnson, L. N.; Acharya, K. R.
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1996Glucofuranose analogues of hydantocidinBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Johnson, L. N.; Crook, S.; Lilley, Pmdq; Watkin, D. J.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Χρυσίνα, Ευαγγελία Δ.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1996A galactopyranose analogue of hydantocidinBrandstetter, T. W.; Wormald, M. R.; Dwek, R. A.; Butters, T. D.; Platt, F. M.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1997Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylateKrulle, T.; delaFuente, C.; Pickering, L.; Aplin, R. T.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Nash, R. J.; Griffiths, R. C.; Fleet, G. W. J.
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1997The structure of glycogen phosphorylase b with an alkyl-dihydropyridine-dicarboxylic acid compound, a novel and potent inhibitorΖωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Tsitsanou, K. E.; Λεωνίδας, Δημήτρης Δ.; Χρυσίνα, Ευαγγελία Δ.; Skamnaki, V. T.; Bischoff, H.; Goldmann, S.; Watson, K. A.; Johnson, L. N.
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1997Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylasedelaFuente, C.; Krulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1997Stereospecific synthesis of spirohydantoins of beta-glucopyranose: Inhibitors of glycogen phosphorylaseKrulle, T. M.; delaFuente, C.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Οικονομάκος, Νίκος Γ.; Fleet, G. W. J.
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1998Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase bHeightman, T. D.; Vasella, A.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Skamnaki, V. T.; Οικονομάκος, Νίκος Γ.
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1999Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbox ylateΟικονομάκος, Νίκος Γ.; Tsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Skamnaki, V. T.; Goldmann, S.; Bischoff, H.
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1999Molecular recognition in glycogen phosphorylase inhibitor designTsitsanou, K. E.; Ζωγράφος, Σπύρος Ε.; Skamnaki, V. T.; Οικονομάκος, Νίκος Γ.
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1999Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structureTsitsanou, K. E.; Οικονομάκος, Νίκος Γ.; Ζωγράφος, Σπύρος Ε.; Skamnaki, V. T.; Gregoriou, M.; Watson, K. A.; Johnson, L. N.; Fleet, G. W. J.
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2000Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor siteΟικονομάκος, Νίκος Γ.; Schnier, J. B.; Ζωγράφος, Σπύρος Ε.; Skamnaki, V. T.; Tsitsanou, K. E.; Johnson, L. N.
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