Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Structural correlations and melting of B-DNA fibers
Δημιουργός/Συγγραφέας:	Wildes, Andrew [EL] Θεοδωρακόπουλος, Νίκος[EN] Theodorakopoulos, Nikos Valle-Orero, Jessica Cuesta-Lopez, Santiago Garden, Jean-Luc Peyrard, Michel
Εκδότης:	American Physical Society
Τόπος έκδοσης:	College Pk
Ημερομηνία:	2011-06-30
Γλώσσα:	Αγγλικά
ISSN:	1539-3755
DOI:	10.1103/PhysRevE.83.061923
Περίληψη:	Despite numerous attempts, understanding the thermal denaturation of DNA is still a challenge due to the lack of structural data on the transition since standard experimental approaches to DNA melting are made in solution and do not provide spatial information. We report a measurement using neutron scattering from oriented DNA fibers to determine the size of the regions that stay in the double-helix conformation as the melting temperature is approached from below. A Bragg peak from the B form of DNA is observed as a function of temperature and its width and integrated intensity are measured. These results, complemented by a differential calorimetry study of the melting of B-DNA fibers as well as electrophoresis and optical observation data, are analyzed in terms of a one-dimensional mesoscopic model of DNA.
Τίτλος πηγής δημοσίευσης:	Physical Review E
Τόμος/Κεφάλαιο:	83
Τεύχος:	6
Σελίδες:	[11]
Θεματική Κατηγορία:	[EL] Φυσική[EN] Physics
Λέξεις-Κλειδιά:	Physics, Fluids & Plasmas Physics, Mathematical
Αξιολόγηση από ομότιμους (peer reviewed):	Ναι
Όροι και προϋποθέσεις δικαιωμάτων:	This article may be downloaded for personal use only. Any other use requires prior permission of the author and American Physical Society (APS). This article appears in "Phys. Rev. E, V83, Issue 6, 061923 – Published 30 June 2011" and can be found at the following URL on the APS website: https://journals.aps.org/pre/abstract/10.1103/PhysRevE.83.061923
Σημειώσεις:	Part 1
Εμφανίζεται στις συλλογές:	Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο