Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Melting Transition of Oriented DNA Fibers Submerged in Poly(ethylene glycol) Solutions Studied by Neutron Scattering and Calorimetry
Δημιουργός/Συγγραφέας:	González A. Wildes A. Marty-Roda M. Cuesta-López S. Mossou E. Studer A. Demé B. Moiroux G. Garden J.-L. [EL] Θεοδωρακόπουλος, Νίκος[EN] Theodorakopoulos, Nikos Peyrard M.
Εκδότης:	American Chemical Society
Ημερομηνία:	2018
Γλώσσα:	Αγγλικά
ISSN:	1520-6106
DOI:	10.1021/acs.jpcb.7b11608
Άλλο:	PubMed ID: 29412656
Περίληψη:	The influence of molecular confinement on the melting transition of oriented Na-DNA fibers submerged in poly(ethylene glycol) (PEG) solutions has been studied. The PEG solution exerts an osmotic pressure on the fibers which, in turn, is related to the DNA intermolecular distance. Calorimetry measurements show that the melting temperature increases and the width of the transition decreases with decreasing intermolecular distance. Neutron scattering was used to monitor the integrated intensity and width of a Bragg peak from the B-form of DNA as a function of temperature. The data were quantitatively analyzed using the Peyrard-Bishop-Dauxois model. The experiments and analysis showed that long segments of double-stranded DNA persist until the last stages of melting and that there appears to be a substantial increase of the DNA dynamics as the melting temperature of the DNA is approached.
Τίτλος πηγής δημοσίευσης:	Journal of Physical Chemistry B
Τόμος/Κεφάλαιο:	122
Τεύχος:	9
Σελίδες:	2504-2515
Θεματική Κατηγορία:	[EL] Φυσική και θεωρητική χημεία[EN] Physical and theoretical chemistry
Αξιολόγηση από ομότιμους (peer reviewed):	Ναι
Κάτοχος πνευματικών δικαιωμάτων:	© 2018 American Chemical Society.
Σημειώσεις:	project “Advanced Materials and Device” (MIS 5002409, NSRF 2014-2020) co-financed by Greece and the European Regional Development Fund.
Εμφανίζεται στις συλλογές:	Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο