Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Plasma Carotenoids, tocopherols, and retinol in the age-stratified (35-74 years) general population: A cross-sectional study in six European countries
Δημιουργός/Συγγραφέας:	Stuetz W. Weber D. Dollé M.E.T. Jansen E. Grubeck-Loebenstein B. Fiegl S. Toussaint O. Bernhardt J. [EL] Γκόνος, Ευστάθιος[EN] Gonos, Efstathios S. Franceschi C. Sikora E. Moreno-Villanueva M. Breusing N. Grune T. Bürkle A.
Εκδότης:	MDPI AG
Ημερομηνία:	2016
Γλώσσα:	Αγγλικά
ISSN:	2072-6643
DOI:	10.3390/nu8100614
Άλλο:	PubMed ID: 27706032
Περίληψη:	Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels. Significant correlations with age were observed for lycopene (r = −0.248), α-tocopherol (r = 0.208), α-carotene (r = −0.112), and β-cryptoxanthin (r = 0.125; all p < 0.001). Age was inversely associated with lycopene (−6.5% per five-year age increase) and this association remained in the multiple regression model with the significant predictors (covariables) being country, season, cholesterol, gender, smoking status, body mass index (BMI (kg/m2)), and dietary habits. The positive association of α-tocopherol with age remained when all covariates including cholesterol and use of vitamin supplements were included (1.7% vs. 2.4% per five-year age increase). The association of higher β-cryptoxanthin with higher age was no longer statistically significant after adjustment for fruit consumption, whereas the inverse association of α-carotene with age remained in the fully adjusted multivariable model (−4.8% vs. −3.8% per five-year age increase). We conclude from our study that age is an independent predictor of plasma lycopene, α-tocopherol, and α-carotene.
Τίτλος πηγής δημοσίευσης:	Nutrients
Τόμος/Κεφάλαιο:	8
Τεύχος:	10
Θεματική Κατηγορία:	[EL] Βιολογία (Γενικά)[EN] Biology (General)
Λέξεις-Κλειδιά:	Age Carotenoids Europe Lycopene Micronutrients Plasma Retinol Tocopherols
Αξιολόγηση από ομότιμους (peer reviewed):	Ναι
Κάτοχος πνευματικών δικαιωμάτων:	© 2016 by the authors; licensee MDPI, Basel, Switzerland.
Όροι και προϋποθέσεις δικαιωμάτων:	All Open Access, Gold, Green
Σημειώσεις:	Seventh Framework Programme, FP7: 200880
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο