Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	MARK-AGE biomarkers of ageing
Δημιουργός/Συγγραφέας:	Bürkle A. Moreno-Villanueva M. Bernhard J. Blasco M. Zondag G. Hoeijmakers J.H.J. Toussaint O. Grubeck-Loebenstein B. Mocchegiani E. Collino S. [EL] Γκόνος, Ευστάθιος[EN] Gonos, Efstathios S. Sikora E. Gradinaru D. Dollé M. Salmon M. Kristensen P. Griffiths H.R. Libert C. Grune T. Breusing N. Simm A. Franceschi C. Capri M. Talbot D. Caiafa P. Friguet B. Slagboom P.E. Hervonen A. Hurme M. Aspinall R.
Εκδότης:	Elsevier Ireland Ltd
Ημερομηνία:	2015
Γλώσσα:	Αγγλικά
ISSN:	0047-6374
DOI:	10.1016/j.mad.2015.03.006
Άλλο:	PubMed ID: 25818235
Περίληψη:	Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation.
Τίτλος πηγής δημοσίευσης:	Mechanisms of Ageing and Development
Τόμος/Κεφάλαιο:	151
Σελίδες:	2-12
Θεματική Κατηγορία:	[EL] Βιολογία (Γενικά)[EN] Biology (General)
Λέξεις-Κλειδιά:	Ageing biomarkers Human studies MARK-AGE
Αξιολόγηση από ομότιμους (peer reviewed):	Ναι
Κάτοχος πνευματικών δικαιωμάτων:	© 2015 The Authors.
Όροι και προϋποθέσεις δικαιωμάτων:	All Open Access, Hybrid Gold, Green
Σημειώσεις:	Seventh Framework Programme, FP7 large-scale integrating project “European Study to Establish Biomarkers of Human Ageing” (MARK-AGE; grant agreement no.: 200880 ), European Commission, EC
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο