Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	β-Cyclodextrin as carrier of novel antioxidants: A structural and efficacy study
Δημιουργός/Συγγραφέας:	Chatzidaki, Maria Kostopoulou, Ioanna Kourtesi, Chryssa Pitterou, Ioanna Avramiotis, Spyridon [EL] Ξενάκης, Αριστοτέλης[EN] Xenakis, Aristotelis Detsi, Anastasia
Ημερομηνία:	2020
Γλώσσα:	Αγγλικά
ISSN:	09277757
DOI:	10.1016/j.colsurfa.2020.125262
Περίληψη:	Antioxidants are radical scavengers that have been proposed to be involved in many pathological conditions, from aging to degenerative disorders. The aim of the present study is the preparation, structural characterization and antioxidant efficacy evaluation of inclusion complexes (ICs) of two synthetic antioxidants with β-CD. The compounds under study are heterocyclic hybrid molecules, which combine the quinolinone framework and the pyrazoline moiety in one molecular scaffold. The ICs were thoroughly investigated in terms of structure using various techniques such as DLS, NMR, FT-IR, TGA and DSC. The findings revealed a different structural profile between the two ICs. Furthermore, the ICs were examined for their ability to scavenge radicals such as DPPH and 4-hydroxy-TEMPO in ethanol medium. Overall, β-CD could act as a promising host for the synthesized antioxidants as it increases their water solubility without inhibiting their radical scavenging ability.
Τίτλος πηγής δημοσίευσης:	Colloids and Surfaces A: Physicochemical and Engineering Aspects
Τόμος/Κεφάλαιο:	603
Θεματική Κατηγορία:	[EL] Χημική τεχνολογία[EN] Chemical technolgy [EL] Χημεία (Γενικά)[EN] Chemistry (General)
Λέξεις-Κλειδιά:	Inclusion complex Quinolinone - pyrazoline hybrids NMR FT-IR Antioxidant activity
Κάτοχος πνευματικών δικαιωμάτων:	Copyright © 2020 Elsevier B.V. All rights reserved
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://www.sciencedirect.com/science/article/abs/pii/S0927775720308554?via%3Dihub
Ηλεκτρονική διεύθυνση περιοδικού (link) :	https://www.sciencedirect.com/journal/colloids-and-surfaces-a-physicochemical-and-engineering-aspects
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο