Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Development of a Multi-Enzymatic Approach for the Modification of Biopolymers with Ferulic Acid
Δημιουργός/Συγγραφέας:	Giannakopoulou, Archontoula Tsapara, Georgia Troganis, Anastassios N Koralli, Panagiota [EL] Χώχος, Χρήστος[EN] Chochos, Christos Polydera, Angeliki C Katapodis, Petros Barkoula, Nektaria-Marianthi Stamatis, Haralambos
Ημερομηνία:	2022-07-17
Γλώσσα:	Αγγλικά
ISSN:	2218-273X
DOI:	10.3390/biom12070992
Άλλο:	35883548
Περίληψη:	A series of polymers, including chitosan (CS), carboxymethylcellulose (CMC) and a chitosan-gelatin (CS-GEL) hybrid polymer, were functionalized with ferulic acid (FA) derived from the enzymatic treatment of arabinoxylan through the synergistic action of two enzymes, namely, xylanase and feruloyl esterase. Subsequently, the ferulic acid served as the substrate for laccase from Agaricus bisporus (AbL) in order to enzymatically functionalize the above-mentioned polymers. The successful grafting of the oxidized ferulic acid products onto the different polymers was confirmed through ultraviolet-visible (UV-Vis) spectroscopy, attenuated total reflectance (ATR) spectroscopy, scanning electron microscopy (SEM) and nuclear magnetic resonance (NMR) spectroscopy. Additionally, an enhancement of the antioxidant properties of the functionalized polymers was observed according to the DDPH and ABTS protocols. Finally, the modified polymers exhibited strong antimicrobial activity against bacterial populations of Escherichia coli BL21DE3 strain, suggesting their potential application in pharmaceutical, cosmeceutical and food industries.
Τίτλος πηγής δημοσίευσης:	Biomolecules
Τόμος/Κεφάλαιο:	12
Τεύχος:	7
Θεματική Κατηγορία:	[EL] Χημική Βιολογία[EN] Chemical Biology [EL] Χημικά προϊόντα: Παραγωγή, χρήση κλπ[EN] Chemicals: Manufacture, use etc. [EL] Φαρμακευτική τεχνολογία[EN] Pharmaceutical technology [EL] Βιοχημεία[EN] Biochemistry [EL] Φασματοσκοπία[EN] Spectroscopy
Λέξεις-Κλειδιά:	Cellulose Gelatin Feruloyl esterase Xylanase Laccase Ferulic acid Enzymatic cross-linking Antioxidant activity Aantimicrobial activity Chitosan
EU Grant:	RESEARCH–CREATE-INNOVATE
EU Grant identifier:	T2EDK-01410
Κάτοχος πνευματικών δικαιωμάτων:	© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
Όροι και προϋποθέσεις δικαιωμάτων:	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://www.mdpi.com/2218-273X/12/7/992
Εμφανίζεται στις συλλογές:	Ινστιτούτο Χημικής Βιολογίας - Επιστημονικό έργο