Εξειδίκευση τύπου :	Κεφάλαιο βιβλίου
Τίτλος:	Parameters affecting the APIs release profile from polymersomes
Δημιουργός/Συγγραφέας:	Kompocholi, Eleni Triantafyllopoulou, Efstathia Lagopati, Nefeli [EL] Πίσπας, Στέργιος[EN] Pispas, Stergios Gazouli, Maria Pippa, Natassa
Ημερομηνία:	2024
Γλώσσα:	Αγγλικά
ISBN:	9780323911115
DOI:	10.1016/B978-0-323-91111-5.00011-1
Περίληψη:	Polymersomes have received a lot of attention lately due to their unique and novel properties as nanocarriers and their stimuli-responsive behavior. Used as drug delivery systems, polymersomes are consisted of amphiphilic block copolymers that are self-assembled into vesicles, forming a bilayer. Therefore, these carriers have the ability to encapsulate both hydrophilic and hydrophobic active pharmaceutical ingredients (APIs). The present study aims to cover a range of reasons and parameters that affect the release profile of the encapsulated APIs from polymersomes. A lot of research that has been carried out so far was analyzed and the factors that influence the drug release behavior are presented in a systematic and detailed way. Furthermore, a comprehensive analysis of the commonly used preparation protocols and characterization techniques is conducted. Finally, the APIs that are mostly encapsulated in polymersomes are thoroughly described. To the best of the authors’ knowledge, this is one of the few reviews that collectively discuss about the release profile of the APIs and the release properties of polymersomes.
Τίτλος πηγής δημοσίευσης:	From Current to Future Trends in Pharmaceutical Technology
Τόμος/Κεφάλαιο:	11
Σελίδες:	391-422
Θεματική Κατηγορία:	[EL] Φαρμακευτική τεχνολογία[EN] Pharmaceutical technology [EL] Φαρμακευτική χημεία[EN] Pharmaceutical chemistry
Λέξεις-Κλειδιά:	polymersomes pharmaceutical ingredients (APIs) nanocarriers
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://doi.org/10.1016/B978-0-323-91111-5.00011-1
Εμφανίζεται στις συλλογές:	Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο