Εξειδίκευση τύπου :	Κεφάλαιο βιβλίου
Τίτλος:	Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications
Δημιουργός/Συγγραφέας:	Selianitis, Dimitrios Sentoukas, Theodore Skandalis, Athanasios Balafouti, Anastasia Pippa, Natassa [EL] Πίσπας, Στέργιος[EN] Pispas, Stergios
Ημερομηνία:	2023
Γλώσσα:	Αγγλικά
ISBN:	9780323913768
DOI:	10.1016/B978-0-323-91376-8.00013-6
Περίληψη:	Liposomes are known to be promising nanoparticles (NPs) for drug delivery applications. Among different types of self-assembled NPs, liposomes stand out for their non-toxic nature, and their possession of dual hydrophilic-hydrophobic domains. Advantages of liposomes include the ability to solubilize hydrophobic drugs, the ability to incorporate different hydrophilic and lipophilic drugs at the same time, lessening the exposure of host organs to potentially toxic drugs and allowing modification of the surface by a variety of different chemical groups. This modification of the surface, or of the individual constituents, may be used to achieve two important goals. Firstly, ligands for active targeting can be attached that are recognized by cognate receptors over-expressed on the target cells of tissues. Secondly, modification can be used to impart a stimulus-responsive or "smart" character to the liposomes, whereby the cargo is released on demand only when certain internal stimuli (pH, reducing agents, specific enzymes) or external stimuli (light, magnetic field or ultrasound) are present. Here, we review the field of smart liposomes for drug delivery applications.
Τίτλος πηγής δημοσίευσης:	Novel Platforms for Drug Delivery Applications
Τόμος/Κεφάλαιο:	9
Θεματική Κατηγορία:	[EL] Φαρμακευτική[EN] Pharmacy and materia medica [EL] Κυτταρολογία[EN] Cytology
Λέξεις-Κλειδιά:	liposomes drug delivery external/internal stimuli nanocarriers smart stimulus-responsive
Ηλεκτρονική διεύθυνση στον εκδότη (link):	https://doi.org/10.1016/B978-0-323-91376-8.00013-6
Εμφανίζεται στις συλλογές:	Ινστιτούτο Θεωρητικής και Φυσικής Χημείας (ΙΘΦΧ) - Επιστημονικό έργο