Εξειδίκευση τύπου :	Άρθρο σε επιστημονικό περιοδικό
Τίτλος:	Molecularly imprinted polymers for cholecystokinin C-terminal pentapeptide recognition
Δημιουργός/Συγγραφέας:	Papaioannou, E.H. Liakopoulou-Kyriakides, M. Papi, R.M. [EL] Κυριακίδης, Δ.Α.[EN] Kyriakidis, D.A.
Εκδότης:	WILEY-V C H VERLAG GMBH
Ημερομηνία:	2007-12
Γλώσσα:	Αγγλικά
ISSN:	1022-1352
DOI:	10.1002/macp.200700371
Περίληψη:	Molecularly imprinted polymers (MIPs) have been prepared from methacrylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) as the functional monomer and crosslinker, respectively, for cholecystokinin C terminal pentapeptide (CCK-5), and screened for their rebinding characteristics. They were produced with alterations in the molar ratio of template/monomer/ crosslinker and the percentage of net rebinding and the imprinting factor (IF) were used for the evaluation of their imprinting efficacy. The dissociation constant values determined in the case of the polymers with better characteristics, further confirmed the results above. Scanning electron microscopy (SEM) images of MIPs were also obtained in an attempt to correlate their characteristics with polymer's morphology. Rebinding experiments with CCK-5 and CCK-8 peptides in the case of the polymer that presented higher performance, with net rebinding values 11.9 and 9%, respectively, indicated that this polymer may be a good candidate for the analysis of CCKrelated peptides. © 2007 WILEY-VCH Verlag GmbH & Co. KGaA.
Τίτλος πηγής δημοσίευσης:	Macromolecular Chemistry and Physics
Τόμος/Κεφάλαιο:	208
Τεύχος:	24
Σελίδες:	2621-2627
Λέξεις-Κλειδιά:	cholecystokinin-C terminal pentapeptide copolymerization molecular imprinting morphology radical polymerization
Κάτοχος πνευματικών δικαιωμάτων:	© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Ηλεκτρονική διεύθυνση περιοδικού (link) :	http://www3.interscience.wiley.com/journal/117932055/grouphome
Εμφανίζεται στις συλλογές:	Άλλα