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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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2006Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studiesWhittamore, P. R. O.; Addie, M. S.; Bennett, S. N. L.; Birch, A. M.; Butters, M.; Godfrey, L.; Kenny, P. W.; Morley, A. D.; Murray, P. M.; Oikonomakos, Nikos G.; Otterbein, L. R.; Pannifer, A. D.; Parker, J. S.; Readman, K.; Siedlecki, P. S.; Schofield, P.; Stocker, A.; Taylor, M. J.; Townsend, L. A.; Whalley, D. P.; Whitehouse, J.
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2005Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding siteChrysina, Evangelia D.; Kosmopoulou, M. N.; Tiraidis, C.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Hadady, Z.; Somsak, L.; Docsa, T.; Gergely, P.; Oikonomakos, Nikos G.
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2007In the search of glycogen phosphorylase inhibitors: 4. Synthesis of C-D-glycopyranosylbenzo(hydro)quinones - Inhibition of and binding to glycogen phosphorylase in the crystalHe, L.; Zhang, Y. Z.; Tanoh, M.; Chen, G. R.; Praly, J. P.; Chrysina, Evangelia D.; Tiraidis, C.; Kosmopoulou, M.; Leonidas, Demetres D.; Oikonomakos, Nikos G.
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2006Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside siteHampson, L. J.; Arden, C.; Agius, L.; Ganotidis, M.; Kosmopoulou, M. N.; Tiraidis, C.; Elemes, Y.; Sakarellos, C.; Leonidas, Demetres D.; Oikonomakos, Nikos G.
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2004Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b - Comparison with ligand binding to pCDK2-cyclin A complexKosmopoulou, M. N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Bischler, N.; Eisenbrand, G.; Sakarellos, C. E.; Pauptit, R.; Oikonomakos, Nikos G.
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2005Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studiesChrysina, Evangelia D.; Kosmopoulou, M. N.; Kardakaris, R.; Bischler, N.; Leonidas, Demetres D.; Kannan, T.; Loganathan, D.; Oikonomakos, Nikos G.
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2006The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: An intermediate conformation with T-State and R-State featuresLukacs, C. M.; Oikonomakos, Nikos G.; Crowther, R. L.; Hong, L. N.; Kammlott, R. U.; Levin, W.; Li, S.; Liu, C. M.; Lucas-McGady, D.; Pietranico, S.; Reik, L.
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1998Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase bHeightman, T. D.; Vasella, A.; Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Oikonomakos, Nikos G.
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1979Effect of Polycarboxylates on Phosphorylase-BSotiroudis, Theodore G.; Oikonomakos, Nikos G.; Evangelopoulos, A. E.
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1988Uridine(5')Diphospho(1)-Alpha-D-Glucose - a Binding Study to Glycogen Phosphorylase-B in the CrystalOikonomakos, Nikos G.; Acharya, K. R.; Stuart, D. I.; Melpidou, A. E.; McLaughlin, P. J.; Johnson, L. N.
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