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Τύπος | Ημερομηνία | Τίτλος | Δημιουργός | Πλήρες κείμενο |
| 1996 | Characterisation, crystallisation and preliminary X-ray diffraction analysis of a Fab fragment of a rat monoclonal antibody with very high affinity for the human muscle acetylcholine receptor | Kontou, M.; Vatzaki, E. H.; Kokla, A.; Acharya, K. R.; Oikonomakos, Nikos G.; Tzartos, S. J. | |
| 1997 | The structure of glycogen phosphorylase b with an alkyl-dihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor | Zographos, Spyros E.; Oikonomakos, Nikos G.; Tsitsanou, K. E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Skamnaki, V. T.; Bischoff, H.; Goldmann, S.; Watson, K. A.; Johnson, L. N. | |
| 1997 | Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate | Krulle, T.; delaFuente, C.; Pickering, L.; Aplin, R. T.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Nash, R. J.; Griffiths, R. C.; Fleet, G. W. J. | |
| 1997 | Stereospecific synthesis of spirohydantoins of beta-glucopyranose: Inhibitors of glycogen phosphorylase | Krulle, T. M.; delaFuente, C.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J. | |
| 1997 | Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylase | delaFuente, C.; Krulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J. | |
| 1997 | The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition | Lowe, E. D.; Noble, M. E. M.; Skamnaki, V. T.; Oikonomakos, Nikos G.; Owen, D. J.; Johnson, L. N. | |
| 1998 | Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase b | Heightman, T. D.; Vasella, A.; Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Oikonomakos, Nikos G. | |
| 1998 | Sugar mimics from sugar lactones | Fleet, G. W. J.; Estevez, J. C.; Smith, M. D.; Bleriot, Y.; de la Fuente, C.; Krulle, T. M.; Besra, G. S.; Brennan, P. J.; Nash, R. J.; Johnson, L. N.; Oikonomakos, Nikos G.; Stalmans, W. | |
| 1998 | The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 angstrom resolution and 100 K: The role of the water structure and its contribution to binding | Gregoriou, M.; Noble, M. E. M.; Watson, K. A.; Garman, E. F.; Krulle, T. M.; De la Fuente, C.; Fleet, G. W. J.; Oikonomakos, Nikos G.; Johnson, L. N. | |
| 1999 | Molecular recognition in glycogen phosphorylase inhibitor design | Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Oikonomakos, Nikos G. | |
| 1999 | Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure | Tsitsanou, K. E.; Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Gregoriou, M.; Watson, K. A.; Johnson, L. N.; Fleet, G. W. J. | |
| 1999 | Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbox ylate | Oikonomakos, Nikos G.; Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Goldmann, S.; Bischoff, H. | |
| 2000 | Structural basis of the synergistic inhibition of glycogen phosphorylase a by caffeine and a potential antidiabetic drug | Tsitsanou, K. E.; Skamnaki, V. T.; Oikonomakos, Nikos G. | |
| 2000 | Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site | Oikonomakos, Nikos G.; Schnier, J. B.; Zographos, Spyros E.; Skamnaki, V. T.; Tsitsanou, K. E.; Johnson, L. N. | |
| 2000 | The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor | Kontou, M.; Leonidas, Demetres D.; Vatzaki, E. H.; Tsantili, P.; Mamalaki, A.; Oikonomakos, Nikos G.; Acharya, K. R.; Tzartos, S. J. | |
| 2000 | Kinetic characterization of the double mutant R148A/E182S of glycogen phosphorylase kinase catalytic subunit: The role of the activation loop | Skamnaki, V. T.; Oikonomakos, Nikos G. | |
| 2000 | A new allosteric site in glycogen phosphorylase b as a target for drug interactions | Oikonomakos, Nikos G.; Skamnaki, V. T.; Tsitsanou, K. E.; Gavalas, N. G.; Johnson, L. N. | |
| 2001 | Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies | Poulas, K.; Eliopoulos, E.; Vatzaki, E.; Navaza, J.; Kontou, M.; Oikonomakos, Nikos G.; Acharya, K. R.; Tzartos, S. J. | |
| 2002 | Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B | Oikonomakos, Nikos G.; Skamnaki, V. T.; Osz, E.; Szilagyi, L.; Somsak, L.; Docsa, T.; Toth, B.; Gergely, P. | |
| 2002 | The 1.76 angstrom resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drug | Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Archontis, G. | |