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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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1999Molecular recognition in glycogen phosphorylase inhibitor designTsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Oikonomakos, Nikos G.
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1995Sulfate-Activated Phosphorylase-B - the Ph-Dependence of Catalytic ActivityZographos, Spyros E.; Oikonomakos, Nikos G.; Dixon, H. B. F.; Griffin, W. G.; Johnson, L. N.; Leonidas, Demetres D.
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1995Specific-Inhibition of Glycogen-Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of GlucopyranoseKrulle, T. M.; Watson, K. A.; Gregoriou, M.; Johnson, L. N.; Crook, S.; Watkin, D. J.; Griffiths, R. C.; Nash, R. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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2002The 1.76 angstrom resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drugOikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, V. T.; Archontis, G.
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1994The design of potential antidiabetic drugs: Experimental investigation of a number of ?-D-glucose analogue inhibitors of glycogen phosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
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1995Glucose Analog Inhibitors of Glycogen-Phosphorylase - from Crystallographic Analysis to Drug Prediction Using Grid Force-Field and Golpe Variable SelectionWatson, K. A.; Mitchell, E. P.; Johnson, L. N.; Cruciani, G.; Son, J. C.; Bichard, C. J. F.; Fleet, G. W. J.; Oikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.
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1996Glucofuranose analogues of hydantocidinBrandstetter, T. W.; delaFuente, C.; Kim, Y. H.; Johnson, L. N.; Crook, S.; Lilley, Pmdq; Watkin, D. J.; Tsitsanou, K. E.; Zographos, Spyros E.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Fleet, G. W. J.
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1994The Design of Potential Antidiabetic Drugs - Experimental Investigation of a Number of Beta-D-Glucose Analog Inhibitors of Glycogen-PhosphorylaseOikonomakos, Nikos G.; Kontou, M.; Zographos, Spyros E.; Tsitoura, H. S.; Johnson, L. N.; Watson, K. A.; Mitchell, E. P.; Fleet, G. W. J.; Son, J. C.; Bichard, C. J. F.; Leonidas, Demetres D.; Acharya, K. R.
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1998Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase bHeightman, T. D.; Vasella, A.; Tsitsanou, K. E.; Zographos, Spyros E.; Skamnaki, V. T.; Oikonomakos, Nikos G.
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2002Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b - Kinetic and crystallographic studiesOikonomakos, Nikos G.; Kosmopoulou, M.; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Somsak, U.; Nagy, V.; Praly, J. P.; Docsa, T.; Toth, A.; Gergely, P.
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