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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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2013Structural analysis of the Rhizoctonia solani agglutinin reveals a domain-swapping dimeric assemblySkamnaki V.T.; Peumans W.J.; Kantsadi A.L.; Cubeta M.A.; Plas K.; Pakala S.; Zographos S.E.; Smagghe G.; Nierman W.C.; Van Damme E.J.M.; Leonidas D.D.
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2014Structure based inhibitor design targeting glycogen phosphorylase b. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylaminesParmenopoulou V.; Kantsadi A.L.; Tsirkone V.G.; Chatzileontiadou D.S.M.; Manta S.; Zographos S.E.; Molfeta C.; Archontis G.; Agius L.; Hayes J.M.; Leonidas D.D.; Komiotis D.
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2015Molecular cloning, carbohydrate specificity and the crystal structure of two Sclerotium rolfsii lectin variantsPeppa V.I.; Venkat H.; Kantsadi A.L.; Inamdar S.R.; Bhat G.G.; Eligar S.; Shivanand A.; Chachadi V.B.; Satisha G.J.; Swamy B.M.; Skamnaki V.T.; Zographos S.E.; Leonidas D.D.
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2014Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: Synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methodsCzifrák K.; Páhi A.; Deák S.; Kiss-Szikszai A.; Kövér K.E.; Docsa T.; Gergely P.; Alexacou K.-M.; Papakonstantinou M.; Leonidas D.D.; Zographos S.E.; Chrysina E.D.; Somsák L.
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2013Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: Comparison of chrysin and flavopiridolTsitsanou K.E.; Hayes J.M.; Keramioti M.; Mamais M.; Oikonomakos N.G.; Kato A.; Leonidas D.D.; Zographos S.E.
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2012N-(4-Substituted-benzoyl)-N '-(beta-D-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methodsVeronika Nagy; Nora Felfoeldi; Balint Konya; Praly, Jean-Pierre; Tibor Docsa; Pal Gergely; Chrysina, Evangelia D.; Tiraidis, Costas; Kosmopoulou, Magda N.; Alexacou, Kyra-Melinda; Konstantakaki, Maria; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Kozmon, Stanislav; Tvaroska, Igor; Laszlo Somsak
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20123 '-Axial CH2OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest WhyManta, Stella; Xipnitou, Andromachi; Kiritsis, Christos; Kantsadi, Anastassia L.; Hayes, Joseph M.; Skamnaki, Vicky T.; Lamprakis, Christos; Kontou, Maria; Zoumpoulakis, Panagiotis; Zographos, Spyros E.; Leonidas, Demetres D.; Komiotis, Dimitri
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2012The s-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase bKantsadi, Anastasia L.; Hayes, Joseph M.; Manta, Stella; Skamnaki, Vicky T.; Kiritsis, Christos; Psarra, Anna-Maria G.; Koutsogiannis, Zissis; Dimopoulou, Athina; Theofanous, Stavroula; Nikoleousakos, Nikolaos; Zoumpoulakis, Panagiotis; Kontou, Maria; Papadopoulos, George; Zographos, Spyros E.; Komiotis, Dimitris; Leonidas, Demetres D.
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2008New Inhibitors of Glycogen Phosphorylase as Potential Antidiabetic AgentsSomsak, L.; Czifrak, K.; Toth, M.; Bokor, E.; Chrysina, Evangelia D.; Alexacou, K. -M.; Hayes, J. M.; Tiraidis, C.; Lazoura, E.; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G.
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2008Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: Synthesis, structure-activity relationships, and X-ray crystallographic studiesWen, Xiaoan; Sun, Hongbin; Liu, Jun; Cheng, Keguang; Zhang, Pu; Zhang, Liying; Hao, Jia; Zhang, Luyong; Ni, Peizhou; Zographos, Spyros E.; Leonidas, Demetres D.; Alexacou, Kyra-Melinda; Gimisis, Thanasis; Hayes, Joseph M.; Oikonomakos, Nikos G.
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