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ΤύποςΗμερομηνίαΤίτλοςΔημιουργόςΠλήρες κείμενο
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1997The structure of glycogen phosphorylase b with an alkyl-dihydropyridine-dicarboxylic acid compound, a novel and potent inhibitorZographos, Spyros E.; Oikonomakos, Nikos G.; Tsitsanou, K. E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Skamnaki, V. T.; Bischoff, H.; Goldmann, S.; Watson, K. A.; Johnson, L. N.
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2012N-(4-Substituted-benzoyl)-N '-(beta-D-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methodsVeronika Nagy; Nora Felfoeldi; Balint Konya; Praly, Jean-Pierre; Tibor Docsa; Pal Gergely; Chrysina, Evangelia D.; Tiraidis, Costas; Kosmopoulou, Magda N.; Alexacou, Kyra-Melinda; Konstantakaki, Maria; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Kozmon, Stanislav; Tvaroska, Igor; Laszlo Somsak
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2008New Inhibitors of Glycogen Phosphorylase as Potential Antidiabetic AgentsSomsak, L.; Czifrak, K.; Toth, M.; Bokor, E.; Chrysina, Evangelia D.; Alexacou, K. -M.; Hayes, J. M.; Tiraidis, C.; Lazoura, E.; Leonidas, Demetres D.; Zographos, Spyros E.; Oikonomakos, Nikos G.
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2008Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2, 3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N '-beta-D-glucopyranosyl urea bindingAlexacou, Kyra-Melinda; Hayes, Joseph M.; Tiraidis, Costas; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Archontis, Georgios; Oikonomakos, Nikos G.; Paul, Jashuva V.; Varghese, Babu; Loganathan, Duraikkannu
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2010Glycogen phosphorylase inhibitor identification targeting the inhibitor binding site using virtual screening and experimental validationZhong, Shijun; Alexacou, Kyra-Melinda; Charavgi, Marianna A.; Tiraidis, Costas; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; MacKerell, Alexander D., Jr.
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2006Indirubin and indigo analogues as potential inhibitors of glycogenolysis: structural basis of glycogen phosphorylase inhibitionOikonomakos, Nikos G.; Kosmopoulou, Magda N.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Tiraidis, Costas; Bischler, Nicolas; Tsitsanou, Katerina E.; Zographos, Spyros E.; Kostas, Ioannis D.; Eisenbrand, Gerhard
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2009Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitorsBenltifa, Mahmoud; Hayes, Joseph M.; Vidal, Sebastien; Gueyrard, David; Goekjian, Peter G.; Praly, Jean-Pierre; Kizilis, Gregory; Tiraidis, Costas; Alexacou, Kyra-Melinda; Chrysina, Evangelia D.; Zographos, Spyros E.; Leonidas, Demetres D.; Archontis, Georgios; Oikonomakos, Nikos G.
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2009Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase caseChrysina, Evangelia D.; Bokor, Eva; Alexacou, Kyra-Melinda; Charavgi, Maria-Despoina; Oikonomakos, George N.; Zographos, Spyros E.; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Laszlo, Somsak
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2010The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitorsAlexacou, Kyra-Melinda; Tenchiu (Deleanu), Alia-Cristina; Chrysina, Evangelia D.; Charavgi, Maria-Despoina; Kostas, Ioannis D.; Zographos, Spyros E.; Oikonomakos, Nikos G.; Leonidas, Demetres D.
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2011Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: Synthesis, enzymatic evaluation and their binding to glycogen phosphorylaseAlexacou, Kyra-Melinda; Zhang, Yun Zhi; Praly, Jean-Pierre; Zographos, Spyros E.; Chrysina, Evangelia D.; Oikonomakos, Nikos G.; Leonidas, Demetres D.
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